18118-29-1

Basic information

• Product Name: 4-[(3-Methyl-2-butenyl)oxy]-3-(3-methyl-2-butenyl)quinoline-2(1H)-one
• Synonyms: 3-(3-Methyl-2-butenyl)-4-[(3-methyl-2-butenyl)oxy]-2(1H)-quinolinone;4-[(3-Methyl-2-butenyl)oxy]-3-(3-methyl-2-butenyl)quinoline-2(1H)-one
• CAS NO: 18118-29-1
• Molecular Formula: C19H23NO2
• Molecular Weight: 297.39
• Mol File: 18118-29-1.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-[(3-Methyl-2-butenyl)oxy]-3-(3-methyl-2-butenyl)quinoline-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(3-Methyl-2-butenyl)oxy]-3-(3-methyl-2-butenyl)quinoline-2(1H)-one(18118-29-1)
• EPA Substance Registry System: 4-[(3-Methyl-2-butenyl)oxy]-3-(3-methyl-2-butenyl)quinoline-2(1H)-one(18118-29-1)

Safety Data

• Hazardous Substances Data: 18118-29-1(Hazardous Substances Data)

Upstream product

• 70254-44-3 2,4-dihydroxyquinoline 
• 870-63-3 prenyl bromide 
• 84017-97-0 3-(1',1'-dimethylallyl)-3-(3,3-dimethylallyl)-1,2,3,4-tetrahydro-2,4-quinoldione 
• 6431-84-1 4-hydroxy-3-(3-methylbut-2-enyl) quinolin-2(1H)one 
• 70254-43-2 4-Hydroxy-2-quinolone 
• 556-82-1 3-methyl-2-buten-1-ol 

Relevant articles and documents

Synthesis and anti-HIV activity of alkylated quinoline 2,4-diols

Naturally occurring quinolone alkaloids, buchapine (1) and compound 2 were synthesized as reported in literature and evaluated for anti-HIV potential in human CD4+ T cell line CEM-GFP, infected with HIV-1NL4.3 virus by p24 antigen capture ELISA

A REVERSIBLE CLAISEN REARRANGEMENT OF 3-(3,3-DIMETHYLALLYL)-4-(3,3-DIMETHYLALLYLOXY)QUINOLIN-2-ONE; SYNTHESIS OF BUCHAPSINE AND LOSS OF ITS 1,1-DIMETHYLALLYL GROUP

Reversible Claisen rearrangement of 3-(3,3-dimethylallyl)-4-(3,3-dimethylallyloxy)quinolin-2-one (5) furnished the alkaloid, buchapsine (6), which readily lost the 1,1-dimethylallyl group; a mechanism for the cleavage reaction is proposed.