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18125-49-0

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18125-49-0 Usage

Uses

Antipyrine (A697500), a non-steroidal anti-inflammatory drug, is widely utilized as a probe for human oxidative drug metabolism. Antipyrine metabolites are formed by various hepatic cytochrome P450 enzymes. 3-Hydroxymethylantipyrine is a metabolite of Antipyrine.

Check Digit Verification of cas no

The CAS Registry Mumber 18125-49-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,1,2 and 5 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 18125-49:
(7*1)+(6*8)+(5*1)+(4*2)+(3*5)+(2*4)+(1*9)=100
100 % 10 = 0
So 18125-49-0 is a valid CAS Registry Number.
InChI:InChI=1/C11H12N2O2/c1-12-10(8-14)7-11(15)13(12)9-5-3-2-4-6-9/h2-7,14H,8H2,1H3

18125-49-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-(hydroxymethyl)-1-methyl-2-phenylpyrazol-3-one

1.2 Other means of identification

Product number -
Other names 3-Hydroxymethyl-antipyrine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:18125-49-0 SDS

18125-49-0Relevant articles and documents

An improved synthesis of 3-hydroxymethylantipyrine using antipyrine as starting material

Buijs,Van Meeteren-Walchli,Breimer,Van der Gen

, p. 419 - 421 (2007/10/02)

A partly new synthesis of 3-hydroxymethylantipyrine, an important metabolite of antipyrine in man and therefore frequently used as a reference substance, is described. The use of tri-n-butyltin hydride to reduce the vinyl bromide system in 3-hydroxymethyl

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