181265-77-0Relevant academic research and scientific papers
Silver(I)- and Base-Mediated formal [4+3] Cycloaddition of in Situ generated 1,2-Diaza-1,3-dienes with C,N-Cyclic Azomethine Imines: An Efficient Protocol for the Synthesis of Tetrazepine Derivatives
Li, Zefei,Li, Shuaikang,Kan, Tianjiao,Wang, Xinyue,Xin, Xin,Hou, Yunlei,Gong, Ping
, p. 2626 - 2631 (2020)
A silver(I)- and base-mediated formal [4+3] cycloaddition reaction of in situ generated 1,2-diaza-1,3-dienes with in situ formed C,N-cyclic azomethine imines has been developed. This protocol provided an efficient method for the synthesis of biologically important 1,2,4,5-tetrazepine derivatives with a wild substrate scope and excellent functional group tolerance in moderate to excellent yields. (Figure presented.).
Pyridinium 1,4-zwitterionic thiolates as a useful class of sulfur-containing synthons: application to the synthesis of 2,5-dihydro-1,4,5-thiadiazepines
Cheng, Bin,Li, Yuntong,Wang, Taimin,Zhang, Xinping,Li, Hui,Li, Yun,Zhai, Hongbin
supporting information, p. 14606 - 14608 (2019/12/11)
A novel [4+3] cascade cyclization reaction of pyridinium 1,4-zwitterionic thiolates with azoalkenes derived from α-halo hydrazones in situ has been developed. This reaction was found to allow expedient access to an array of 2,5-dihydro-1,4,5-thiadiazepine
Cycloaddition reactions of nitrosoalkenes, azoalkenes and nitrile oxides mediated by hydrotalcite
Lemos, Americo,Lourenco, Joao P.
experimental part, p. 170 - 182 (2010/08/20)
Mg:Al 3:1 hydrotalcite (Ht), used in catalytic quantities, promotes the generation of nitrosoalkenes, azoalkenes and nitrile oxides. These can be intercepted in situ by heterocycles and olefins in [4+2] and [3+2] cycloaddition reactions, producing dihydro
