181269-87-4

Basic information

• Product Name: CIS-4-HYDROXY-PIPERIDINE-1,2-DICARBOXYLIC ACID1-TERT-BUTYL ESTER 2-METHYL ESTER
• Synonyms: CIS-4-HYDROXY-PIPERIDINE-1,2-DICARBOXYLIC ACID1-TERT-BUTYL ESTER 2-METHYL ESTER;1-(tert-Butyl) 2-methyl (2S,4R)-4-hydroxy-tetrahydro-1,2(2H)-pyridinedicarboxylate;(2S,4R)-1-Tert-butyl2-Methyl4-hydroxypiperidine-1,2-dicarbo xylate;1-tert-Butyl (2S,4R)-2-Methyl4-hydroxypiperidine-1,2-dicarboxylate;1-tert-Butyl 2-methyl cis-4-hydroxypiperidine-1,2-dicarboxylate 95+%;Methyl cis-4-hydroxypiperidine-2-carboxylate, N-BOC protected, cis-1-(tert-Butoxycarbonyl)-4-hydroxy-2-(methoxycarbonyl)piperidine;1-tert-butyl 2-methyl (2S,4R)-rel-4-hydroxypiperidine-1,2-dicarboxylate
• CAS NO: 181269-87-4
• Molecular Formula: C12H21NO5
• Molecular Weight: 259.29884
• Mol File: 181269-87-4.mol
• Article Data: 15

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: CIS-4-HYDROXY-PIPERIDINE-1,2-DICARBOXYLIC ACID1-TERT-BUTYL ESTER 2-METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: CIS-4-HYDROXY-PIPERIDINE-1,2-DICARBOXYLIC ACID1-TERT-BUTYL ESTER 2-METHYL ESTER(181269-87-4)
• EPA Substance Registry System: CIS-4-HYDROXY-PIPERIDINE-1,2-DICARBOXYLIC ACID1-TERT-BUTYL ESTER 2-METHYL ESTER(181269-87-4)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 181269-87-4(Hazardous Substances Data)

Usage

General Description

The chemical CIS-4-HYDROXY-PIPERIDINE-1,2-DICARBOXYLIC ACID1-TERT-BUTYL ESTER 2-METHYL ESTER is a compound with a complex structure. It contains a piperidine ring with a hydroxyl group and two carboxylic acid groups, as well as a tert-butyl ester and a methyl ester. CIS-4-HYDROXY-PIPERIDINE-1,2-DICARBOXYLIC ACID1-TERT-BUTYL ESTER 2-METHYL ESTER is likely to have various pharmaceutical and industrial applications, potentially as a building block for the synthesis of other compounds or as a ligand in coordination chemistry. Its specific properties and potential uses would depend on its interactions with other chemicals and biological systems.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 211058-81-0 methyl (2R,4S)-4-hydroxy-2-piperidinecarboxylate 
• 211058-80-9 methyl 4(R)-hydroxypiperidine-2(S)-carboxylate 
• 403503-37-7 (2S,4R)-1-benzyl 2-methyl 4-hydroxypiperidine-1,2-dicarboxylate 
• 198646-60-5 (S)-1-(tertbutyloxycarbonyl)-4-oxo-piperidine-2-carboxylic acid 
• 1799811-83-8 1-(tert-butyl)-2-methyl-(S)-4-oxopiperidine-1,2-dicarboxylate 
• 81357-18-8 4-oxo-piperidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester 
• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 
• 97231-88-4 1-(tert-butoxycarbonyl)-4-(tert-butyldimethylsilyl)oxypiperidine 
• 1391042-08-2 1-(tert-butoxycarbonyl)-4-(tert-butyldimethylsilyl)oxypiperidine-2-carboxylic acid methyl ester 
• 1391042-07-1 1-(tert-butoxycarbonyl)-4-(tert-butyldimethylsilyl)oxypiperidine-2-carboxylic acid 
• 5382-16-1 4-HYDROXYPIPERIDINE 
• 144913-66-6 4-hydroxy-2-piperidine carboxylic acid methyl ester 
• 1103929-22-1 methyl (2S,4R)-4-hydroxy-1-((R)-1-phenylethyl)piperidine-2-carboxylate 

Downstream Products

• 164298-41-3 1-tert-butyl 2-methyl (+/-)-3,6-dihydro-1,2(2H)-pyridinedicarboxylate 
• 1448668-02-7 C₁₉H₂₇NO₅ 
• 1448668-03-8 C₂₈H₂₉NO₄ 
• 1448667-65-9 (2S,4S)-4-(benzyloxy)-1-(2,2-diphenylacetyl)piperidine-2-carboxylic acid 
• 1448667-66-0 (2S,4R)-4-(benzyloxy)-1-(2,2-diphenylacetyl)piperidine-2-carboxylic acid 
• 1448668-26-5 C₃₀H₂₈FNO₄ 
• 211058-80-9 methyl 4(R)-hydroxypiperidine-2(S)-carboxylate 
• 1448668-04-9 (2S,4R)-methyl 1-(2,2-diphenylacetyl)-4-hydroxypiperidine-2-carboxylate 
• 1448668-05-0 C₂₈H₂₉NO₄ 
• 1448668-18-5 C₃₀H₂₉NO₄ 
• 1432130-53-4 C₁₆H₂₃NO₆S 
• 1432130-57-8 C₂₃H₂₉NO₈S₂ 
• 1432130-61-4 C₂₂H₂₉NO₇S₂ 

Relevant articles and documents

Synthesis of all isomers of pulcherrimine, a bitter principle in the sea urchin ovary

All eight isomers of pulcherrimine, a bitter principle of the sea urchin (Hemicentrotus pulcherrimus) ovary have been synthesized, which led to revision of the absolute stereochemistry of pulcherrimine. The synthetic pulcherrimine and the 2S isomer were highly bitter at a concentration of 1.0 mM.

Substituted piperidine amide derivative, preparation method thereof, and application of derivative to pharmacy

The invention relates to a substituted piperidine amide derivative as shown in a general formula (I) or a stereisomer and pharmaceutically acceptable salt thereof, a preparation method of the derivative, medicinal combination as well as application of the derivative to the aspects of local anaesthesia or analgesia. The definition of each group of the general formula (I) is consistent with that of the description. (The general formula (I) is as shown in the description).

HETEROCYCLIC COMPOUNDS AND METHODS FOR THEIR USE

The present invention relates to heterocyclic compounds useful for antagonising angiotensin II Type 2 (AT2) receptor. More particularly the invention relates to piperidine compounds, compositions containing them and their use in methods of treating or preventing disorders or diseases associated with AT2 receptor function including neuropathic pain, inflammatory pain, conditions associated with neuronal hypersensitivity, impaired nerve conduction velocity, cell proliferation disorders, disorders associated with an imbalance between bone resorption and bone formation and disorders associated with aberrant nerve regeneration.