181420-00-8

Basic information

• Product Name: N-[2-(3,3-Diethoxy-prop-1-ynyl)-phenyl]-acetamide
• Synonyms: N-[2-(3,3-Diethoxy-prop-1-ynyl)-phenyl]-acetamide
• CAS NO: 181420-00-8
• Molecular Weight: 261.321
• Mol File: 181420-00-8.mol

Chemical Properties

• CAS DataBase Reference: N-[2-(3,3-Diethoxy-prop-1-ynyl)-phenyl]-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[2-(3,3-Diethoxy-prop-1-ynyl)-phenyl]-acetamide(181420-00-8)
• EPA Substance Registry System: N-[2-(3,3-Diethoxy-prop-1-ynyl)-phenyl]-acetamide(181420-00-8)

Safety Data

• Hazardous Substances Data: 181420-00-8(Hazardous Substances Data)

Upstream product

• 10160-87-9 Propiolaldehyde diethyl acetal 
• 19591-17-4 o-iodoacetanilide 

Downstream Products

• 181420-86-0 N-[2-((1Z,3E)-2-Diethoxymethyl-4-trimethylsilanyl-buta-1,3-dienyl)-phenyl]-acetamide 
• 181420-80-4 N-[2-((1Z,3E)-2-Diethoxymethyl-4-phenyl-buta-1,3-dienyl)-phenyl]-acetamide 
• 42925-09-7 3-(p-methylphenyl)-quinoline 
• 181421-88-5 3-(3-fluorophenyl)quinoline 
• 302357-89-7 4-(p-tolyl)quinoline 
• 46870-61-5 4-(4-methoxyphenyl)quinoline 
• 57479-32-0 3-(4-methoxyphenyl)quinoline 
• 61064-99-1 3-<(E)-2-phenylethenyl>-quinoline 
• 22191-98-6 4-(p-aminophenyl)-quinoline 
• 104967-74-0 3-(p-aminophenyl)-quinoline 
• 181420-47-3 N-{2-[(Z)-3,3-Diethoxy-2-(4-methoxy-phenyl)-propenyl]-phenyl}-acetamide 
• 107915-36-6 3-(p-hydroxyphenyl)-quinoline 

Relevant articles and documents

Palladium-catalysed hydroarylation and hydrovinylation of 3,3-dialkoxy-1-aryl-1-propynes. An approach to 3-aryl- and 3-vinylquinolines

Acetylenic acetals and ketals have been reacted with aryl and vinyl halides to generate hydroarylation and hydrovinylation products. The reaction proceeds with high regioselectivity. The carbopalladation step appears to be mainly controlled by steric effects and the new carbon-carbon bond is generated preferentially on the carbon bearing the acetal group. The reaction has been employed to develop a regioselective synthesis of 3-aryl and 3-vinylquinolines.