181473-13-2

Upstream product

• 578-66-5 8-amino quinoline 
• 21815-91-8 3-chlorobenzo[b]thiophen-2-carbonyl chloride 

Relevant academic research and scientific papers

Structural studies of 3-chloro-N-(8′-quinolyl)×benzo[b] thiophene-2-carboxamide

3-Chloro-N-(8′-quinolyl)benzo[b]thiophene-2-carboxamide was synthesized from 3-chlorobenzo[b] thiophene -2-carboxyl chloride and 8-aminoquinoline in the presence of triethylamine. The single crystal X-ray structure determination confirmed the earlier proposed structure and also characterized by 1HNMR, and Mass spectroscopy. Crystallographic study reveals that the structure crystallizes in monoclinic system, a = 14.878(4) A, b = 8.4292(15) A, c = 25.461(7) A, β = 112.022(18)°, Z = 8, V = 2960.20(12) A3 with space group C2/c (No. 15). In the structure packing, three kinds of interactions are responsible for the stability of the structure. Infinite two-dimensional stair-like layered chains are formed by relatively strong intermolecular hydrogen bonds [C14-H14...O1]. These parallel chains are connected by several π-π and CH-π interactions, alternatively. There are two such parallel chains with 70.53°, which are in contact by van der Waals interactions. Copyright

Synthesis and total 1H-NMR assignment of [1]benzothieno-[2,3-c] [1,10] phenanthroline

The synthesis of [1]benzothieno[2,3-c][l,10]phenanthroline (5) is described. It was obtained in four steps from known starting materials. The basic skeleton of the molecule and of the phenanthroline ring were formed via photocyclization. The total assignment of 1H-nmr spectra was accomplished with the aid of two-dimensional nmr methods.