181477-28-1 Usage
Structure
Halogenated indane derivative with bromine and amino group
Uses
Research chemical, intermediate in organic compound synthesis
Pharmacological properties
Potential ligand for CNS receptors
Utilization
Development of pharmaceutical drugs
Production
Through various synthetic methods
Handling
Caution required due to potential toxicity
Properties
Interesting chemical and biological properties, subject of scientific investigation
Check Digit Verification of cas no
The CAS Registry Mumber 181477-28-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,1,4,7 and 7 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 181477-28:
(8*1)+(7*8)+(6*1)+(5*4)+(4*7)+(3*7)+(2*2)+(1*8)=151
151 % 10 = 1
So 181477-28-1 is a valid CAS Registry Number.
181477-28-1Relevant articles and documents
Structure based evolution of a novel series of positive modulators of the AMPA receptor
Jamieson, Craig,MacLean, John K.F.,Brown, Christopher I.,Campbell, Robert A.,Gillen, Kevin J.,Gillespie, Jonathan,Kazemier, Bert,Kiczun, Michael,Lamont, Yvonne,Lyons, Amanda J.,Moir, Elizabeth M.,Morrow, John A.,Pantling, John,Rankovic, Zoran,Smith, Lynn
, p. 805 - 811 (2011)
Starting from compound 1, we utilized biostructural data to successfully evolve an existing series into a new chemotype with a promising overall profile, exemplified by 19.