889362-93-0

Upstream product

• 501-53-1 benzyl chloroformate 
• 181477-28-1 (S)-(+)-5-Bromo-2-aminoindane 
• 370861-57-7 (S)-5-bromo-2-aminoindan (1R)-(-)-10-camphorsulfonate salt 
• 321352-52-7 5-bromo-2-aminoindane hydrobromide 
• 2338-18-3 2-aminoindane hydrochloride 

Downstream Products

• 889362-92-9 (S)-(5-isobutyl-indan-2-yl)-carbamic acid benzyl ester 
• 1403324-91-3 (S)-benzyl 5-amino-2,3-dihydro-1H-inden-2-yl([²H₅]ethyl)carbamate 
• 1403324-92-4 (R)-benzyl 2-benzamido-6,7-dihydro-5H-indeno[5,6-d]thiazol-6-yl([²H₅]ethyl)carbamate 
• 1403324-93-5 (R)-N-(6-([²H₅]ethylamino)-6,7-dihydro-5H-indeno[5,6-d]thiazol-2-yl)benzamide 
• 1403324-90-2 (S)-benzyl 5-bromo-2,3-dihydro-1H-inden-2-yl([²H₅]ethyl)carbamate 
• 1199828-07-3 (S)-benzyl 5-(hydroxymethyl)-2,3-dihydro-1H-inden-2-ylcarbamate 
• 1251457-90-5 C₁₈H₁₈ClNO₂ 
• 1199828-09-5 (S)-benzyl-5-((4-(hydroxymethyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)methyl)-2,3-dihydro-1H-inden-2-ylcarbamate 
• 1199828-69-7 (S)-N-(5-((4-(hydroxymethyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)methyl)-2,3-dihydro-1H-inden-2-yl)-2-chlorobenzenesulfonamide 
• 1199828-87-9 (S)-ethyl 1-((2-(benzyloxycarbonylamino)-2,3-dihydro-1H-inden-5-yl)methyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate 
• 1199828-05-1 (S)-methyl 2-(benzyloxycarbonylamino)-2,3-dihydro-1H-indene-5-carboxylate 

Relevant academic research and scientific papers

Structure based evolution of a novel series of positive modulators of the AMPA receptor

Starting from compound 1, we utilized biostructural data to successfully evolve an existing series into a new chemotype with a promising overall profile, exemplified by 19.

INDANE DERIVATIVES AS AMPA RECEPTOR MODULATORS

The present invention relates to a heterocyclic derivative according to formula (I); wherein the variables are defined as in the specification, or to a pharmaceutically acceptable salt or solvate thereof. The present invention also relates to a pharmaceut

D2 Receptor Ligand-078

This invention relates to the compound of Formula I and pharmaceutically acceptable salts thereof: (R)-N*6*-ethyl-6,7-dihydro-5H-indeno[5,6-d]thiazole-2,6-diamine This invention also relates to methods of making, methods of using, and pharmaceutical compo

5-HYDROXY-BENZOTHIAZOLE DERIVATIVES HAVING BETA-2-ADRENORECPTOR AGONIST ACTIVITY

Compounds of formula (I) in free or salt or solvate form, wherein T has the meaning as indicated in the specification, are useful for treating conditions that are prevented or alleviated by activation of the β2-adrenoreceptor. Pharmaceutical co