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2,2,2-Trifluoro-1-(7-nitro-3,4-dihydro-1H-isoquinolin-2-yl)-ethanone, commonly referred to as TNIQ, is a chemical compound characterized by its molecular formula C11H8F3N2O3. This yellow to orange solid has a molecular weight of 272.18 g/mol. TNIQ is recognized for its potent and selective inhibition of nitric oxide synthase (NOS), a property that positions it as a potential therapeutic agent for addressing neurodegenerative diseases and inflammatory conditions. Its capacity to modulate the production of nitric oxide, a critical signaling molecule in physiological and pathological processes, has been extensively studied, making TNIQ a valuable research tool for investigating NOS-related mechanisms and for the development of drugs targeting NOS-mediated pathways.

181514-37-4

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181514-37-4 Usage

Uses

Used in Pharmaceutical Development:
TNIQ is utilized as a therapeutic agent for the treatment of neurodegenerative diseases and inflammatory conditions due to its ability to inhibit nitric oxide synthase (NOS), a key enzyme involved in the production of nitric oxide.
Used in Research Applications:
TNIQ serves as a research tool for studying the mechanisms related to nitric oxide synthase (NOS) and for the development of drugs that target NOS-mediated pathways, which are implicated in various physiological and pathological processes.
Used in Drug Discovery:
In the field of drug discovery, TNIQ is employed as a lead compound for the development of new pharmaceuticals that can modulate the activity of nitric oxide synthase, potentially offering novel treatments for a range of conditions influenced by NOS activity.
Used in Neurodegenerative Disease Treatment:
TNIQ is applied as a potential treatment for neurodegenerative diseases, leveraging its NOS inhibitory properties to mitigate the effects of excessive nitric oxide production, which is often associated with such conditions.
Used in Inflammatory Condition Management:
In the management of inflammatory conditions, TNIQ is used to reduce inflammation by inhibiting the production of nitric oxide, a molecule that can contribute to the inflammatory response.

Check Digit Verification of cas no

The CAS Registry Mumber 181514-37-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,1,5,1 and 4 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 181514-37:
(8*1)+(7*8)+(6*1)+(5*5)+(4*1)+(3*4)+(2*3)+(1*7)=124
124 % 10 = 4
So 181514-37-4 is a valid CAS Registry Number.

181514-37-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 7-nitro-1,2,3,4-tetrahydro-2-trifluoroacetylisoquinoline

1.2 Other means of identification

Product number -
Other names 2,2,2-trifluoro-1-(7-nitro-3,4-dihydro-1H-isoquinolin-2-yl)-ethanone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:181514-37-4 SDS

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