711601-13-7Relevant academic research and scientific papers
1, 2 - DIHYDRO- 3H- PYRAZOLO [3, 4 - D] PYRIMIDIN -3 - ONE ANALOGS
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Paragraph 0149, (2019/02/15)
Compounds of Formula (I) are provided herein. Such compounds, as well as pharmaceutically acceptable salts and compositions thereof, are useful for treating diseases or conditions, including conditions characterized by excessive cellular proliferation, such as breast cancer.
Evaluation of a series of anticonvulsant 1,2,3,4-tetrahydroisoquinolinyl-benzamides
Chan, Wai N.,Hadley, Michael S.,Harling, John D.,Herdon, Hugh J.,Orlek, Barry S.,Riley, Graham J.,Stead, Rachel E. A.,Stean, Tania O.,Thompson, Mervyn,Upton, Neil,Ward, Robert W.
, p. 2085 - 2094 (2007/10/03)
SAR studies around a series of N-(tetrahydroisoquinolinyl)-2-methoxybenzamides, identified by high-throughput screening at the novel SB-204269 binding site, have provided compounds such as 13, 29-33 with high affinity and excellent anticonvulsant activity in animal models. Copyright (C) 2000 Elsevier Science Ltd.
