181641-61-2

Basic information

• Product Name: 1-(BENZYLOXYCARBONYL)-4-PHENYLPIPERIDINE-4-CARBOXYLIC ACID
• Synonyms: 4-phenyl-1-phenylmethoxycarbonylpiperidine-4-carboxylic acid
• CAS NO: 181641-61-2
• Molecular Formula: C₂₀H₂₁NO₄
• Molecular Weight: 339.38504
• Mol File: 181641-61-2.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(BENZYLOXYCARBONYL)-4-PHENYLPIPERIDINE-4-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(BENZYLOXYCARBONYL)-4-PHENYLPIPERIDINE-4-CARBOXYLIC ACID(181641-61-2)
• EPA Substance Registry System: 1-(BENZYLOXYCARBONYL)-4-PHENYLPIPERIDINE-4-CARBOXYLIC ACID(181641-61-2)

Safety Data

• Hazardous Substances Data: 181641-61-2(Hazardous Substances Data)

Usage

General Description

1-(Benzyloxycarbonyl)-4-phenylpiperidine-4-carboxylic acid is a chemical compound that belongs to the class of piperidine carboxylic acids. It is a white solid with a molecular formula C24H24N2O4. 1-(BENZYLOXYCARBONYL)-4-PHENYLPIPERIDINE-4-CARBOXYLIC ACID is commonly used as a precursor in the synthesis of various pharmaceuticals and other organic compounds due to its reactivity and versatility. It is important in the production of certain drugs as it serves as an intermediate in the synthesis of other complex chemical compounds.

Upstream product

• 501-53-1 benzyl chloroformate 
• 3627-45-0 4-phenyl-piperidine-4-carboxylic acid 
• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 
• 37586-22-4 4-benzoylpiperidine 
• 96067-93-5 benzyl 4-(hydroxydiphenylmethyl)-piperidine-1-carboxylate 
• 916976-36-8 4-benzhydrylidene-piperidine-1-carboxylic acid benzyl ester 
• 922504-27-6 4-benzoylpiperidine-1-carboxylic acid benzyl ester 
• 916976-41-5 4-benzoyl-4-phenyl-piperidine-1-carboxylic acid benzyl ester 

Downstream Products

• 674791-74-3 C₁₈H₃₄N₂O*ClH 
• 674791-73-2 C₁₈H₂₈N₂O*ClH 
• 674791-72-1 C₂₆H₃₄N₂O₃ 
• 181641-81-6 1-(Benzyloxycarbonyl)-4-(chloroformyl)-4-phenylpiperidine 
• 3627-45-0 4-phenyl-piperidine-4-carboxylic acid 

Relevant articles and documents

UREIDE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES

This invention relates to a pharmaceutical comprising, as an active ingredient, a ureide derivative represented by formula: or a pharmaceutically acceptable salt thereof. The ureide derivative or a pharmaceutically acceptable salt thereof according to the present invention is useful for relieving pain and treating or preventing neuropathic pain.

CAN-mediated rearrangement of 4-benzhydrylidenepiperidines

Several 1-substituted phenyl-(4-phenylpiperidin-4-yl)methanones are synthesized in modest overall yields starting from the reaction of different 1-substituted 4-benzhydrylidenepiperidines via CAN-mediated rearrangement. This facile strategy was also used to synthesize meperidine analog.

Ureidopiperidine derivatives as selective human NK3 receptor antagonists

The invention concerns compounds of formula (I) in racemic or optically pure form, methods for obtaining them and pharmaceutical compositions containing same. Said compounds are selective NK3receptor antagonists.