181655-83-4Relevant academic research and scientific papers
Cyclic-fused azomethine-, imidate-, and thioimidate methylides: An efficient regiocontrolled entry into spiro-fused pyrrolidines
Fishwick, Colin W.G.,Foster, Richard J.,Carr, Robin E.
, p. 5163 - 5166 (1996)
Generation of azomethine ylides, imidate methylides, and thioimidate methylides which are exocyclic to indane, benzofuran, benzothiophene, and benzopyran moieties respectively, in the presence of electron deficient dipolarophiles, gives direct access to s
Scope and applications of second generation palladium-catalyzed cycloalkenylation. Stereoselective total syntheses of isoiridomyrmecin, isodihydronepetalactone, and α-skytanthine
Takeda, Kazutaka,Toyota, Masahiro
experimental part, p. 9909 - 9921 (2012/02/06)
Functionalized bicyclo[3.2.1]octanes, -oxabicyclo-[4.3.0]nonanes, 3-azabicyclo[3.3.0]octanes, and 3-azabicyclo[4.3.0]nonanes were easily synthesized via a second generation palladium-catalyzed cycloalkenylation. Isoiridomyrmecin and isodihydronepetalactone, both of which feature a 3-oxabicyclo[4.3.0]nonane subunit, were stereoselectively synthesized via a second generation palladium-catalyzed cycloalkenylation as the key step. α-Skytanthine, a typical 3-azabicyclo[4.3.0]nonane alkaloid, was also constructed using the same catalytic cyclization protocol.
