18168-82-6Relevant academic research and scientific papers
Guanidine compound for preventing and treating chronic pain medication (by machine translation)
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Paragraph 0106-0110, (2020/08/27)
The invention relates to a guanidine compound as shown in general formula (I) as a guanidine compound for preventing and treating chronic pain disease. A pharmaceutically acceptable salt thereof, a prodrug thereof, a solvate thereof, a deuterated substanc
An efficient five-component synthesis of thioether containing dihydropyrano[2,3-c]pyrazoles: a green domino strategy
Ramesh, Vediyappan,Shanmugam, Sivakumar,Devi, Natarajan Savitha
, p. 9993 - 10001 (2016/12/07)
An efficient route for the synthesis of novel thioether containing dihydropyrano[2,3-c]pyrazoles has been accomplished via a solvent-free, catalyst-free, one-pot, five component domino strategy. This synthetic approach offers several advantages such as an easy work-up, no need for purification techniques and a short reaction time with good atom economy and high yields of the products (81-86%).
A facile synthesis and discovery of highly functionalized tetrahydropyridines and pyridines as antimycobacterial agents
Raju, Suresh Kumar,Stephen, Michael Rajesh,Subbu, Perumal,Debjani, Banerjee,Perumal, Yogeeswari,Dharmarajan, Sriram
scheme or table, p. 602 - 610 (2010/08/20)
The four-component reaction of ethyl-3-oxo-4-(arylsulfanyl)butanoate, substituted aromatic aldehydes and ammonium acetate afforded novel ethyl 4-hydroxy-2,6-diaryl-5-(arylsulfanyl)-1,2,5,6-tetrahydro-3-pyridinecarboxylates. These tetrahydro-pyridine ester
Synthesis of functionalized diaryl sulfides based on regioselective one-pot cyclizations of 1,3-bis(trimethylsilyloxy)-1,3-butadienes
Rashid, Muhammad A.,Rasool, Nasir,Adeel, Muhammad,Reinke, Helmut,Fischer, Christine,Langer, Peter
, p. 3782 - 3793 (2008/09/20)
Functionalized diaryl sulfides were prepared based on one-pot cyclizations of 1,3-bis(trimethylsilyloxy)-1,3-butadienes.
Synthesis and in vitro anti-hepatitis B virus activities of some ethyl 5-hydroxy-1H-indole-3-carboxylates
Zhao, Chunshen,Zhao, Yanfang,Chai, Huifang,Gong, Ping
, p. 2552 - 2558 (2007/10/03)
A series of ethyl 5-hydroxy-1H-indole-3-carboxylates 6A-10 T were synthesized and evaluated for their anti-hepatitis B virus (HBV) activities in 2.2.15 cells. The IC50 and selective index of inhibition on replication of HB
The Synthesis of the Monomethyl Isomers of Benzonaphththiophene
Tominaga, Yoshinori,Pratap, Ram,Castle, Raymond N.,Lee, Milton L.
, p. 859 - 863 (2007/10/02)
All isomers of the monomethylbenzonaphththiophenes were synthesized using photocyclization of 3-styrylbenzothiophenes.The 1-, 3-, 4-, and 5-methylbenzonaphthothiophenes were synthesized by irradiation of the corresponding methylated
