181706-01-4Relevant academic research and scientific papers
Syntheses and structure-activity relationships of the second-generation antitumor taxoids: Exceptional activity against drug-resistant cancer cells
Ojima, Iwao,Slater, John C.,Michaud, Evelyne,Kuduk, Scott D.,Bounaud, Pierre-Yves,Vrignaud, Patricia,Bissery, Marie-Christine,Veith, Jean M.,Pera, Paula,Bernacki, Ralph J.
, p. 3889 - 3896 (2007/10/03)
A series of new 3'-(2-methyl-1-propenyl) and 3'-(2-methylpropyl) taxoids with modifications at C-10 was synthesized by means of the β-lactam synthon method using 10-modified 7-(triethylsilyl)-10-deacetylbaccatin III derivatives. The new taxoids thus synth
