181713-49-5Relevant academic research and scientific papers
BiCl3-catalysed nucleophilic substitution of Baylis-Hillman adducts with alcohols
Li, Jian,Liu, Xiaotao,Zhao, Peichao,Jia, Xueshun
experimental part, p. 159 - 162 (2009/05/30)
An efficient nucleophilic substitution of Baylis-Hillman adducts with alcohols catalysed by 10 mol% BiCI3, affords functionalised ethers. Water was the only side product.
FeCl3-catalyzed nucleophilic substitution of Baylis-Hillman adducts with alcohols
Jia, Xueshun,Zhao, Peichao,Liu, Xiaotao,Li, Jian
, p. 1617 - 1628 (2008/09/20)
FeCl3-catalyzed nucleophilic substitution reaction of Baylis-Hillman adducts with alcohols is described. The present protocol allows for the efficient syntheses of many kinds of functional ethers. This conversion is also a green route because water is the only side product. Copyright Taylor & Francis Group, LLC.
1,4-asymmetric induction in the chromium(II)- and indium-mediated coupling of allyl bromides to aldehydes
Maguire, Robert J.,Mulzer, Johann,Bats, Jan W.
, p. 6936 - 6940 (2007/10/03)
A series of allyl bromides bearing an ethereal stereogenic substituent at C-2 were synthesized from methyl acrylate. These were coupled with a range of aldehydes under chromium(II) chloride-mediated conditions to afford syn-4-alkoxyalkan-1-ols in good yie
1,4-Asymmetric induction in the Nozaki-Hiyama reaction
Maguire, Robert J.,Mulzer, Johann,Bats, Jan W.
, p. 5487 - 5490 (2007/10/03)
A series of allyl bromides 3a-c bearing a stereogenic carbon substituent at C-2 are synthesized in four steps from methyl acrylate. These are found to react with aldehydes, mediated by chromium(II) chloride, to furnish syn-4-alkoxyalkan-1-ols 4 in good to
