181717-64-6

Upstream product

• 13154-24-0 triisopropylsilyl chloride 
• 873-75-6 4-bromobenzenemethanol 
• 6485-79-6 chlorotriisopropylsilane 
• 1122-91-4 4-bromo-benzaldehyde 

Downstream Products

• 195454-03-6 1-(Bromomethyl-dimethyl-silanyl)-4-triisopropylsilanyloxymethyl-benzene 
• 337510-99-3 N,N-diethyl-4-triisopropylsilanyloxymethylbenzamide 
• 337511-00-9 N,N-diethyl-2-formyl-4-triisopropylsilanyloxymethylbenzamide 
• 337511-03-2 3-[2-(4-methoxy-benzyloxymethyl)-buta-1,3-dienyl]-5-triisopropylsilanyloxymethyl-1,3-dihydroisobenzofuran-1-ol 
• 337511-02-1 3-[2-(4-methoxy-benzyloxymethyl)-buta-1,3-dienyl]-5-triisopropylsilanyloxymethyl-3H-isobenzofuran-1-one 
• 337511-04-3 3-[2-(1-hydroxy-2-methylallyl)-5-triisopropylsilanyloxymethylphenyl]-3-(4-methoxy-benzyloxymethyl)-penta-2,4-dien-1-ol 
• 337511-01-0 N,N-diethyl-2-[1-hydroxy-3-(4-methoxy-benzyloxymethyl)-penta-2,4-dienyl]-4-triisopropylsilanyloxymethylbenzamide 
• 195454-24-1 3-[(4-Hydroxymethyl-phenyl)-dimethyl-silanyl]-propionic acid 
• 195454-12-7 3-[(4-Hydroxymethyl-phenyl)-dimethyl-silanyl]-propionic acid methyl ester 
• 195454-13-8 3-[(4-Formyl-phenyl)-dimethyl-silanyl]-propionic acid methyl ester 
• 195454-23-0 2-{[(4-Hydroxymethyl-phenyl)-dimethyl-silanyl]-methyl}-malonic acid dimethyl ester 
• 195454-06-9 3-(4-{[(4-Formyl-phenyl)-dimethyl-silanyl]-methoxy}-phenyl)-propionic acid methyl ester 
• 195454-14-9 3-[(4-{[2-(4-Hydroxy-phenyl)-ethylamino]-methyl}-phenyl)-dimethyl-silanyl]-propionic acid methyl ester 
• 195454-05-8 3-(4-{[(4-Hydroxymethyl-phenyl)-dimethyl-silanyl]-methoxy}-phenyl)-propionic acid methyl ester 

Relevant academic research and scientific papers

Preparation method 4 - hydroxymethylphenylboronic acid

The invention relates to the technical field of organic synthesis. The invention specifically discloses a preparation method of 4 -hydroxymethylphenylboronic acid. To the preparation method, bromobenzyl alcohol is taken as a raw material, Grignard reagent

Breaking C-O Bonds with Uranium: Uranyl Complexes as Selective Catalysts in the Hydrosilylation of Aldehydes

We report herein the possibility to perform the hydrosilylation of carbonyls using actinide complexes as catalysts. While complexes of the uranyl ion [UO2]2+ have been poorly considered in catalysis, we show the potentialities of the Lewis acid [UO2(OTf)2] (1) in the catalytic hydrosilylation of a series of aldehydes. [UO2(OTf)2] proved to be a very active catalyst affording distinct reduction products depending on the nature of the reductant. With Et3SiH, a number of aliphatic and aromatic aldehydes are reduced into symmetric ethers, while iPr3SiH yielded silylated alcohols. Studies of the reaction mechanism led to the isolation of aldehyde/uranyl complexes, [UO2(OTf)2(4-Me2N-PhCHO)3], [UO2(μ-κ2-OTf)2(PhCHO)]n, and [UO2(μ-κ2-OTf)(κ1-OTf)(PhCHO)2]2, which have been fully characterized by NMR, IR, and single-crystal X-ray diffraction.

ETHYNYLBENZENE DERIVATIVES

Disclosed are compounds of formulae (I), (II), and (II)I: and pharmaceutically acceptable salts thereof, wherein the variables, R, R1, R2, R3, R101, L, D, Q, Y, X, and Z are defined herein. These compounds are useful for treating Gram-negative bacteria infections.

Syntheses of trans -SCH-A and cis -SCH-A via a stereodivergent cyclopropanation protocol

(Figure Presented) A highly diastereoselective cyclopropanation protocol has been employed in the syntheses of trans-SCH-A and cis-SCH-A. This strategy encompasses a stereodivergent procedure for the preparation of syn- and anti-cyclopropane diastereoisom

Benzobicyclo[8.4.0.1,608,13]tetradecenones: Ring CD-taxoid models by planar tether controlled cycloaddition

(matrix presented) A general approach to functionalized hexahydroanthracene dione skeletons is described. The planar dicarbonyl triene 15 cyclized spotaneously upon oxidation of the precursor diol 14 to the tricyclicdiketone 16. The adducts 16 and 2 were

Simple Silyl Linker for the Solid Phase Organic Synthesis of Aryl-Containing Molecules

We have designed a simple (dimethylsilyl)propionic acid linker for the solid phase synthesis of aryl-containing organic compounds. The linker is cleaved smoothly with trifluoroacetic acid either in solution or in the vapor phase to release the unsubstituted aryl moiety. Using this linker, we have successfully demonstrated the solid phase synthesis of a test compound which involved alkylation, acylation, and Mitsunobu reactions.