181764-33-0

Upstream product

• 866398-21-2 1-(1,1-dimethylheptyl)-3-methoxybenzene 
• 628-44-4 2-methyl-2-octanol 
• 100863-37-4 1-(3-methoxyphenyl)heptan-1-one 
• 106591-04-2 1-(3-methoxyphenyl)heptan-1-ol 
• 591-31-1 3-methoxy-benzaldehyde 
• 91-10-1 1,3-dimethoxy-2-hydroxy-benzene 
• 866398-16-5 trifluoromethanesulfonic acid 4-(1,1-dimethylheptyl)-2,6-dimethoxyphenyl ester 
• 866398-19-8 trifluoromethanesulfonic acid 3-(1,1-dimethylheptyl)-5-methoxyphenyl ester 
• 60526-81-0 1-(1',1'-dimethylheptyl)-3,5-dimethoxybenzene 
• 87613-50-1 3-(1,1-dimethylheptyl)-5-methoxyphenol 
• 60526-69-4 4-(1,1-dimethylheptyl)-2,6-dimethoxyphenol 

Downstream Products

• 866398-11-0 (1R,3R,4R)-3-[4-(1,1-dimethylheptyl)-2-methoxyphenyl]-4-(3-hydroxypropyl)cyclohexanol 
• 866398-05-2 (1R,4R,5R,8S)-4-[4-(1,1-dimethylheptyl)-2-methoxyphenyl]-8-methoxymethoxybicyclo[3.3.1]non-3-en-2-one 
• 866398-09-6 3-{(7R,8R)-7-[4-(1,1-dimethylheptyl)-2-methoxyphenyl]-1,4-dioxaspiro[4,5]dec-8-yl}propan-1-ol 
• 866398-07-4 (7R,8R)-7-[4-(1,1-dimethylheptyl)-2-methoxyphenyl]-8-(2-[1,3]dioxolan-2-ylethyl)-1,4-dioxaspiro[4,5]decane 
• 83002-04-4 CP 55,940 
• 1240391-12-1 C₂₂H₃₂O₂ 
• 1374219-15-4 2-methoxy-4-(2-methyloctan-2-yl)phenylboronic acid 
• 1374219-24-5 7-(2-methoxy-4-(2-methyloctan-2-yl)phenyl)-1,4-dioxaspiro[4.5]dec-6-en-8-one 
• 1374219-29-0 C₂₂H₃₆O₂ 
• 1374219-28-9 C₂₅H₄₀O₂ 
• 1026176-11-3 (1S,4R,5S)-4-[4-(1,1-Dimethyl-heptyl)-2-hydroxy-phenyl]-6,6-dimethyl-bicyclo[3.1.1]heptan-2-one 

Relevant academic research and scientific papers

Enantioselective synthesis of (-)-CP-55940 via ruthenium-catalyzed asymmetric hydrogenation of ketones

A new and efficient catalytic asymmetric synthesis of the potent cannabinoid receptor agonist (-)-CP-55940 has been developed by using ruthenium-catalyzed asymmetric hydrogenation of racemic α-aryl ketones via dynamic kinetic resolution (DKR) as a key step. With RuCl2-SDPs/ diamine [SDPs=7,7'-bis(diarylphophino)-1,1'-spirobiindane] catalysts the asymmetric hydrogenation of racemic α-arylcyclohexanones via DKR provided the corresponding cis-β-arylcyclohexanols in high yields with up to 99.3% ee and >99:1 cis-selectivities. Both ethylene ketal group at the cyclohexane ring and ortho-methoxy group at the phenyl ring of the substrates 6 have little effect on the selectivity and reactivity of the hydrogenations. Based on this highly efficient asymmetric ketone hydrogenation, (-)-CP-55940 was synthesized in 13 steps (the longest linear steps) in 14.6% overall yield starting from commercially available 3-methoxybenzaldehyde and 1,4-cyclohexenedione monoethylene acetal. Copyright

Synthesis and pharmacology of 1-methoxy analogs of CP-47,497

Three 1-methoxy analogs of CP-47,497 (7, 8, and 19) have been synthesized and their affinities for the cannabinoid CB1 and CB2 receptors have been determined. Although these compounds exhibit selectivity for the CB2 recept

Expedient synthesis of potent cannabinoid receptor agonist (-)-CP55,940

(Chemical Equation Presented) A stereocontrolled synthesis of (-)-CP55,940, a potent cannabinoid receptor agonist, has been attained using a novel aldolization/retroaldolization interconversion strategy, in which a temporarily generated chiral aldol motif plays essential roles.