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181772-16-7

181772-16-7

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181772-16-7 Usage

Uses

3,5-Bis(trifluoroMethyl)hydrocinnaMic acid can be used to prepare novel biologically active amides.

Check Digit Verification of cas no

The CAS Registry Mumber 181772-16-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,1,7,7 and 2 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 181772-16:
(8*1)+(7*8)+(6*1)+(5*7)+(4*7)+(3*2)+(2*1)+(1*6)=147
147 % 10 = 7
So 181772-16-7 is a valid CAS Registry Number.
InChI:InChI=1/C11H8F6O2/c12-10(13,14)7-3-6(1-2-9(18)19)4-8(5-7)11(15,16)17/h3-5H,1-2H2,(H,18,19)

181772-16-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-[3,5-bis(trifluoromethyl)phenyl]propanoic acid

1.2 Other means of identification

Product number -
Other names 3-(3,5-bis(trifluoromethyl)phenyl)propanoic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:181772-16-7 SDS

181772-16-7Relevant articles and documents

Design, synthesis, and biological evaluation of novel diarylalkyl amides as TRPV1 antagonists

Li, Fu-Nan,Kim, Nam-Jung,Paek, Seung-Mann,Kwon, Do-Yeon,Min, Kyung Hoon,Jeong, Yeon-Su,Kim, Sun-Young,Park, Young-Ho,Kim, Hee-Doo,Park, Hyeung-Geun,Suh, Young-Ger

experimental part, p. 3557 - 3567 (2009/09/27)

We have developed a new class of diarylalkyl amides as novel TRPV1 antagonists. They exhibited potent 45Ca2+ uptake inhibitions in rat DRG neuron. In particular, the amide 59 was identified as a potent antagonist with IC50 of 57 nM. The synthesis and structure-activity relationship of the diarylalkyl amides are also described.

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