181803-09-8

Basic information

• Product Name: (R)-5-((R)-4-Benzyloxy-1-hydroxy-butyl)-dihydro-furan-2-one
• CAS NO: 181803-09-8
• Molecular Weight: 264.321
• Mol File: 181803-09-8.mol

Chemical Properties

• CAS DataBase Reference: (R)-5-((R)-4-Benzyloxy-1-hydroxy-butyl)-dihydro-furan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-5-((R)-4-Benzyloxy-1-hydroxy-butyl)-dihydro-furan-2-one(181803-09-8)
• EPA Substance Registry System: (R)-5-((R)-4-Benzyloxy-1-hydroxy-butyl)-dihydro-furan-2-one(181803-09-8)

Safety Data

• Hazardous Substances Data: 181803-09-8(Hazardous Substances Data)

Upstream product

• 181803-05-4 ethyl (4E)-8-benzyloxy-4-enoctanoate 
• 247200-28-8 (4R,5R)-8-Benzyloxy-4,5-dihydroxy-octanoic acid methyl ester 

Downstream Products

• 1053653-34-1 4-Nitro-benzoic acid (S)-3-((4R,5S)-5-decyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-((2S,5S,2'R)-5'-oxo-octahydro-[2,2']bifuranyl-5-yl)-propyl ester 
• 182072-80-6 (R)-5-[(Z)-(S)-1-(tert-Butyl-diphenyl-silanyloxy)-7-((4R,5R)-5-decyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-hept-4-enyl]-dihydro-furan-2-one 
• 182072-82-8 (R)-5-[(Z)-(S)-1-(tert-Butyl-diphenyl-silanyloxy)-7-((4R,5S)-5-decyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-hept-4-enyl]-dihydro-furan-2-one 
• 181803-29-2 (cis,4R,5R,12R,13R)-5-tert-butyldiphenylsilyloxytricosa-12,13-isopropylidenedioxy-8-en-1,4-olide 
• 182072-81-7 (cis,4R,5R,12R,13S)-5-tert-butyldiphenylsilyloxytricosa-12,13-isopropylidenedioxy-8-en-1,4-olide 
• 303053-15-8 (4R,5R)-8-hydroxy-5-(tert-butyldiphenylsilyloxy)octan-1,4-olide 
• 182072-77-1 (S)-4-(tert-Butyl-diphenyl-silanyloxy)-4-((R)-5-oxo-tetrahydro-furan-2-yl)-butyraldehyde 
• 182072-78-2 (S)-4-(tert-Butyl-diphenyl-silanyloxy)-4-((S)-5-oxo-tetrahydro-furan-2-yl)-butyraldehyde 
• 181803-16-7 (4R,5R)-tert-butyldiphenylsilyloxyoctan-1-al-5,8-olide 
• 182072-76-0 (S)-5-((S)-4-Benzyloxy-1-hydroxy-butyl)-dihydro-furan-2-one 

Relevant articles and documents

Total synthesis of the cytotoxic annonaceous acetogenin (30S)-bullanin

The total synthesis of (+)-(30S)-bullanin, a highly cytotoxic Annonaceous acetogenin, was effected by a convergent approach in which the key core bis-2,2'-tetrahydrofuran stereocenters were introduced through a combination of Sharpless asymmetric dihydroxylation and S(E)2' additions of oxygenated nonracemic allylic stannane and indium reagents to γ-oxygenated aldehydes.