181874-02-2

Basic information

• Product Name: (R)-2-Methyl-3-phenyl-2-(toluene-4-sulfonylamino)-propionic acid methyl ester
• Synonyms: (R)-2-Methyl-3-phenyl-2-(toluene-4-sulfonylamino)-propionic acid methyl ester
• CAS NO: 181874-02-2
• Molecular Weight: 347.435
• Mol File: 181874-02-2.mol

Chemical Properties

• CAS DataBase Reference: (R)-2-Methyl-3-phenyl-2-(toluene-4-sulfonylamino)-propionic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-Methyl-3-phenyl-2-(toluene-4-sulfonylamino)-propionic acid methyl ester(181874-02-2)
• EPA Substance Registry System: (R)-2-Methyl-3-phenyl-2-(toluene-4-sulfonylamino)-propionic acid methyl ester(181874-02-2)

Safety Data

• Hazardous Substances Data: 181874-02-2(Hazardous Substances Data)

Upstream product

• 181874-04-4 trans-(2R,3S)-(+)-N-(p-toluenesulfonyl)-2-methyl-2-carbomethoxy-3-phenylaziridine 
• 181874-01-1 trans-(S_S,2R,3S)-(+)-N-(p-toluenesulfinyl)-2-methyl-2-carbomethoxy-3-phenylaziridine 
• 350479-90-2 (S,E)-N-benzylidene-4-methylbenzenesulfinamide 

Downstream Products

• 38574-55-9 (R)-(-)-methyl 2-amino-2-methyl-3-phenylpropionate 
• 17350-84-4 (R)-2-amino-2-methyl-3-phenylpropanoic acid 

Relevant articles and documents

2-Methyl N-(p-toluenesulfinyl)aziridine-2-carboxylic acid: Asymmetric synthesis of α-methylphenylalanine and α-methyl-β-phenylserine

2-Substituted aziridine 2a, prepared from sulfinimine 1 via a Darzens-type condensation, undergoes a highly regio- and stereocontrolled ring-opening to give α-methylphenylalanine and α-methyl-β-phenylserine in high enantiomeric purity.