38574-55-9

Basic information

• Product Name: (R)-(-)-methyl 2-amino-2-methyl-3-phenylpropionate
• Synonyms: (R)-(-)-methyl 2-amino-2-methyl-3-phenylpropionate
• CAS NO: 38574-55-9
• Molecular Weight: 193.246
• Mol File: 38574-55-9.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: (R)-(-)-methyl 2-amino-2-methyl-3-phenylpropionate(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(-)-methyl 2-amino-2-methyl-3-phenylpropionate(38574-55-9)
• EPA Substance Registry System: (R)-(-)-methyl 2-amino-2-methyl-3-phenylpropionate(38574-55-9)

Safety Data

• Hazardous Substances Data: 38574-55-9(Hazardous Substances Data)

Upstream product

• 17350-84-4 (R)-2-amino-2-methyl-3-phenylpropanoic acid 
• 149-73-5 trimethyl orthoformate 
• 100-39-0 benzyl bromide 
• 120328-90-7 methyl (E)-N-benzylidenealaninate 
• 53933-42-9 2-(benzylidene-amino)-propionic acid methyl ester 
• 50899-67-7 (S)-2-{[1-(4-Methoxy-phenyl)-meth-(E)-ylidene]-amino}-propionic acid methyl ester 
• 91292-73-8 methyl alanine p-chlorobenzaldimine 
• 67-56-1 methanol 
• 946414-68-2 (3R,6S)-3-benzyl-3-methyl-6-isopropyl-piperazine-2,5-dione 
• 91292-73-8 (+/-)-(4-chlorobenzylidene)alanine methyl ester 
• 181874-01-1 trans-(S_S,2R,3S)-(+)-N-(p-toluenesulfinyl)-2-methyl-2-carbomethoxy-3-phenylaziridine 
• 181874-02-2 (R)-2-Methyl-3-phenyl-2-(toluene-4-sulfonylamino)-propionic acid methyl ester 
• 350479-90-2 (S,E)-N-benzylidene-4-methylbenzenesulfinamide 
• 170027-70-0 (S)-2-{[1-Naphthalen-2-yl-meth-(E)-ylidene]-amino}-propionic acid methyl ester 

Downstream Products

• 105582-36-3 C₁₆H₁₉⁽²⁾H₂BrN₂O₂ 
• 105660-86-4 C₁₆H₁₉⁽²⁾H₂BrN₂O₂ 
• 105582-36-3 C₁₆H₁₉⁽²⁾H₂BrN₂O₂ 
• 105582-34-1 C₁₆H₁₉⁽²⁾H₂BrN₂O₂ 
• 105582-34-1 C₁₆H₁₉⁽²⁾H₂BrN₂O₂ 
• 105660-84-2 C₁₆H₁₉⁽²⁾H₂BrN₂O₂ 
• 71785-56-3 (R)-2-Benzyl-3,6-dimethoxy-2,5-dimethyl-2,5-dihydro-pyrazine 
• 105582-33-0 (3R)-(-)-2,5-dimethoxy-3-benzyl-3-methyl-3,6-dihydropyrazine 
• 105582-32-9 (3R)-(-)-3-methyl-3-benzyl-2,5-diketopiperazine 
• 176436-01-4 (R)-2-Methyl-2-((S)-2-methyl-1-phenyl-propoxycarbonylamino)-3-phenyl-propionic acid 
• 176435-86-2 (R)-2-Methyl-2-((R)-2-methyl-1-phenyl-propoxycarbonylamino)-3-phenyl-propionic acid 
• 176435-99-7 (R)-2-Methyl-2-((S)-2-methyl-1-phenyl-propoxycarbonylamino)-3-phenyl-propionic acid methyl ester 
• 176435-83-9 (R)-2-Methyl-2-((R)-2-methyl-1-phenyl-propoxycarbonylamino)-3-phenyl-propionic acid methyl ester 
• 17350-84-4 (R)-2-amino-2-methyl-3-phenylpropanoic acid 

Relevant articles and documents

Influence of aromatic substituents on metal(II)salen catalysed, asymmetric synthesis of α-methyl α-amino acids

The influence of substituents on both the aromatic rings of the catalyst, and the benzylidene unit of the substrate are investigated in the (salen)copper(II) catalysed asymmetric benzylation of alanine derivatives. Catalysts with electron-donating, and el

Asymmetric catalysis of carbon-carbon bond forming reactions using amino acid-derived C1-symmetrical salen ligands

Four amino acids (alanine, valine, phenylalanine and phenylglycine) have been converted into C1-symmetrical salen ligands and complexed to titanium, vanadium, copper and cobalt. The resulting complexes have been used as asymmetric catalysts for asymmetric cyanohydrin synthesis, asymmetric Strecker reactions, asymmetric synthesis of α-methyl amino acids and asymmetric Darzens condensations. Satisfactory levels of asymmetric induction were obtained from reactions in which the (salen)metal complex acts as a chiral Lewis acid, but low levels of asymmetric induction were obtained from reactions carried out under solid-liquid phase-transfer conditions.

Influence of the metal and chiral diamine on metal(II)salen catalysed, asymmetric synthesis of α-methyl α-amino acids

The influence of the metal ion and chiral diamine used to form a metal(salen) complex on the catalytic activity of the complex in the asymmetric benzylation of an alanine enolate was investigated. Only metal ions which could form square-planar complexes g