18189-42-9

Upstream product

• 636-53-3 diethyl isophthalate 
• 201230-82-2 carbon monoxide 
• 58313-23-8 3-iodobenzoic acid methyl ester 
• 64-17-5 ethanol 
• 99-63-8 benzene-1,3-dicarbonyl dichloride 
• 15226-74-1 dicobalt octacarbonyl 
• 585-76-2 m-bromobenzoic acid 
• 124-38-9 carbon dioxide 
• 121-91-5 isophthalic acid 
• 67326-20-9 3-carbethoxybenzoyl chloride 

Downstream Products

• 67326-20-9 3-carbethoxybenzoyl chloride 
• 823195-12-6 3-(3-thiophen-2-yl-[1,2,4]oxadiazol-5-yl)-benzoic acid ethyl ester 
• 862014-10-6 N-prop-2-ynyl-isophthalamic acid ethyl ester 
• 757965-28-9 isophthalic acid mono(N-butylamide) 
• 1247691-89-9 C₁₅H₂₀N₂O₅ 

Relevant academic research and scientific papers

One-pot synthetic method for m-acetylbenzoic acid

The invention relates to a synthetic method, in particular to a one-pot synthetic method for m-acetylbenzoic acid. According to the one-pot synthetic method for the m-acetylbenzoic acid, there is no need to purify an intermediate product. The reaction equation of the m-acetylbenzoic acid is shown in the description, wherein R refers to methyl or ethyl, and R1 refers to methyl or ethyl or n-propyl. Compared with synthetic methods in the prior art, the synthetic method has the advantages that raw materials are low in price and easy to get, reaction conditions are mild, the obtained intermediate product can be directly used for a reaction in a next step without being separated and purified, and therefore process cost is greatly lowered.

Extremely fast gas/liquid reactions in flow microreactors: Carboxylation of short-lived organolithiums

Carboxylation of short-lived organolithiums bearing electrophilic functional groups such as nitro, cyano, and alkoxycarbonyl groups with CO 2 to give carboxylic acids and active esters was accomplished in a flow microreactor system. The successful reactions indicate that gas/liquid mass transfer and the subsequent chemical reaction with CO2 are extremely fast. Carboxylation of short-lived organolithiums bearing electrophilic functional groups such as nitro, cyano, and alkoxycarbonyl groups with CO 2 to give carboxylic acids and active esters was accomplished in a flow microreactor system. The successful reactions indicate that gas/liquid mass transfer and the subsequent chemical reaction with CO2 are extremely fast (see scheme).

Cobalt carbonyl as an effective CO source in one-pot synthesis of esters from aryl halides

For the first time, we have successfully applied Co2(CO) 8 as an effective carbonyl source for the Pd catalysed alkoxycarbonylation of aryl halides affording the corresponding aryl esters under mild microwave conditions. A wide variety of esters and carbonyl derivatives were prepared using this protocol.

Control of helix sense by composition of chiral-achiral copolymers of N-propargylbenzamides

N-Propargylbenzamides 1-7 were polymerized with (nbd)Rh+[η 6-C6H5B-(C6H 5)3] to afford polymers with moderate molecular weights (Mn = 26000-51000) in good y