181929-46-4

Basic information

• Product Name: Carbamic acid, [3-[1-(2,5,6,7-tetrahydro-4-hydroxy-2-oxocyclopenta[b]pyran-3-yl)propyl] phenyl]-, phenylmethyl ester
• CAS NO: 181929-46-4
• Molecular Formula: C25H25NO5
• Molecular Weight: 419.477
• Mol File: 181929-46-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [3-[1-(2,5,6,7-tetrahydro-4-hydroxy-2-oxocyclopenta[b]pyran-3-yl)propyl] phenyl]-, phenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [3-[1-(2,5,6,7-tetrahydro-4-hydroxy-2-oxocyclopenta[b]pyran-3-yl)propyl] phenyl]-, phenylmethyl ester(181929-46-4)
• EPA Substance Registry System: Carbamic acid, [3-[1-(2,5,6,7-tetrahydro-4-hydroxy-2-oxocyclopenta[b]pyran-3-yl)propyl] phenyl]-, phenylmethyl ester(181929-46-4)

Safety Data

• Hazardous Substances Data: 181929-46-4(Hazardous Substances Data)

Upstream product

• 67531-69-5 1-(3-aminophenyl)-1-propanol 
• 17408-16-1 3'-nitropropiophenone 
• 90345-58-7 6,7-Dihydro-4-hydroxycyclopentapyran-2(5H)-on 
• 166337-56-0 [3-(1-Hydroxy-propyl)-phenyl]-carbamic acid benzyl ester 

Downstream Products

• 181930-01-8 3-[1-(3-Amino-phenyl)-propyl]-4-hydroxy-6,7-dihydro-5H-cyclopenta[b]pyran-2-one 

Relevant articles and documents

Cycloalkylpyranones and cycloalkyldihydropyrones as HIV protease inhibitors: Exploring the impact of ring size on structure-activity relationships

Previously, 3-substituted cycloalkylpyranones, such as 2d, have proven to be effective inhibitors of HIV protease. In an initial series of 3-(1- phenylpropyl) derivatives with various cycloalkyl ring sizes, the cyclooctyl analog was the most potent. We be