17408-16-1

Basic information

• Product Name: 3-Nitropropiophenone
• Synonyms: 1-(3-NITROPHENYL)PROPANONE;3''-NITROPROPIOPHENONE 98+%;1-(3-nitrophenyl)propan-1-one;1-(3-Nitrophenyl)-1-propanone;3-nitro-1-phenylpropan-1-one;1-(3-Nitrophenyl)propan-1-one, 3-Propanoylnitrobenzene;3-Nitropropiophenone SynonyMs 3'-Nitropropiophenone;3-Nitro-propylphenone
• CAS NO: 17408-16-1
• Molecular Formula: C₉H₉NO₃
• Molecular Weight: 179.17
• EINECS: 241-435-8
• Product Categories: Carbonyl Compounds;Aromatic Propiophenones (substituted);C9;Carbonyl Compounds;Ketones
• Mol File: 17408-16-1.mol
• Article Data: 5

Chemical Properties

• Melting Point: 98-101 °C(lit.)
• Boiling Point: 254.5 °C at 760 mmHg
• Flash Point: 106.3 °C
• Appearance: /
• Density: 1.199 g/cm³
• Vapor Pressure: 0.0171mmHg at 25°C
• Refractive Index: 1.548
• Storage Temp.: Sealed in dry,Room Temperature
• BRN: 1954069
• CAS DataBase Reference: 3-Nitropropiophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Nitropropiophenone(17408-16-1)
• EPA Substance Registry System: 3-Nitropropiophenone(17408-16-1)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 22-24/25-36-26
• WGK Germany: 3
• Hazardous Substances Data: 17408-16-1(Hazardous Substances Data)

Usage

Uses

3′-Nitropropiophenone was used to study the FTIR and FT Raman spectra in the regions 3500-100 cm(-1).

InChI:InChI=1/C9H9NO3/c1-2-9(11)7-4-3-5-8(6-7)10(12)13/h3-6H,2H2,1H3

Upstream product

• 93-55-0 1-phenyl-propan-1-one 
• 619-24-9 3-nitrobenzonitrile 
• 121-92-6 3-nitrobenzoic acid 
• 25310-92-3 propiophenone dimethyl acetal 

Downstream Products

• 67531-69-5 1-(3-aminophenyl)-1-propanol 
• 1197-05-3 1-(3-amino-phenyl)-propan-1-one 
• 2524-81-4 3-propylaniline 
• 113613-40-4 3-methyl-2-(3-nitrophenyl)-1H-indole 
• 29067-53-6 α-ethyl-3-nitrobenzyl alcohol 
• 23281-57-4 (Z)-1-(3-nitrophenyl)propene 
• 23204-79-7 (E)-1-nitro-3-(prop-1-en-1-yl)benzene 
• 4302-39-0 β-Chlor-m-nitro-α-methyl-zimtaldehyd 
• 81096-33-5 2,3-dimethyl-1-(m-nitrophenyl)-2-buten-1-one 
• 81096-26-6 2,3-dimethyl-3-nitro-1-(m-nitrophenyl)-1-butanone 
• 32780-90-8 (Z)-1-Iod-1-(m-nitrophenyl)propen 
• 1205-36-3 2-bromo-1-(3-nitrophenyl)propan-1-one 
• 618-95-1 methyl 3-nitrobenzoate 

Relevant articles and documents

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Synthesis and evaluation of the anticonvulsant activity of a series of 2-amino-1-phenyl-1-propranols derived from the metabolites of the antidepressant bupropion

A series of 2-amino-1-phenyl-1-propanols that are structurally related to known metabolites of bupropion, 1 (Wellbutrin) were synthesized and evaluated as potential anticonvulsants. The (R*,R*)-2-tert-butylamino-1-(3-trifluoromethylphenyl) propanol 20 had an ED50 of 16.5 ± 2.8 mg/kg ip in mice in the maximal electroshock screen and was chosen for further evaluation.

Ozone-mediated Nitration of Aromatic Ketones and Related Compounds with Nitrogen Dioxide

Alkyl aryl ketones react smoothly with nitrogen dioxide at low temperatures in the presence of ozone to give ortho- and meta-nitro derivatives as the principal products, the former usually being predominant (ortho:meta = 1.1-3.8:1.0).No attack was observed on the alkyl side chains.