182010-52-2

Upstream product

• 1025798-23-5 (E)-6-(6-Acetoxy-4-methanesulfonyloxymethyl-2-methoxy-3-methyl-phenyl)-4-methyl-hex-4-enoic acid methyl ester 
• 1026370-68-2 (E)-6-(6-Acetoxy-4-acetylsulfanylmethyl-2-methoxy-3-methyl-phenyl)-4-methyl-hex-4-enoic acid methyl ester 
• 182010-34-0 (E)-6-(6-Acetoxy-4-hydroxymethyl-2-methoxy-3-methyl-phenyl)-4-methyl-hex-4-enoic acid methyl ester 
• 182010-33-9 (E)-6-(6-Hydroxy-4-hydroxymethyl-2-methoxy-3-methyl-phenyl)-4-methyl-hex-4-enoic acid methyl ester 
• 24280-93-1 mycophenolic acid 
• 31848-65-4 3-(5-Carboxy-3-methyl-pent-2t-enyl)-4-hydroxy-6-hydroxymethyl-2-methoxy-toluol; 6-(6-Hydroxy-4-hydroxymethyl-2-methoxy-3-methyl-phenyl)-4-methyl-hex-4t-ensaeure 
• 182010-51-1 (E)-6-(6-Acetoxy-2-methoxy-3,4-dimethyl-phenyl)-4-methyl-hex-4-enoic acid methyl ester 

Downstream Products

• 182010-66-8 (E)-6-(3-formyl-2-hydroxy-6-methoxy-4,5-dimethylphenyl)-4-methyl-4-hexenoic acid methyl ester 
• 182010-62-4 (E)-6-(2-Hydroxy-6-methoxy-4,5-dimethyl-3-nitro-phenyl)-4-methyl-hex-4-enoic acid methyl ester 
• 182010-56-6 (E)-6-(2-Hydroxy-3-iodo-6-methoxy-4,5-dimethyl-phenyl)-4-methyl-hex-4-enoic acid methyl ester 

Relevant academic research and scientific papers

Structure-activity relationships for inhibition of inosine monophosphate dehydrogenase by nuclear variants of mycophenolic acid

Structure-activity relationships in the region of the phthalide ring of the inosine monophosphate dehydrogenase inhibitor mycophenolic acid have been explored. Replacement of the lactone ring with other cyclic moieties resulted in loss of potency, especia