182066-12-2

Upstream product

• 61-54-1 tryptamine 
• 182066-02-0 3-[2-((2S,3R,4R,5R)-3,4-Bis-benzyloxy-5-hydroxy-2-hydroxymethyl-piperidin-1-yl)-ethyl]-indole-1-carboxylic acid tert-butyl ester 
• 182066-01-9 3,4-di-O-benzyl-1,5-dideoxy-1,5-[2'-(1H-indol-3-yl)-ethyl]-imino-L-gulitol 
• 157363-85-4 1,2:5,6-Dianhydro-3,4-di-O-benzyl-D-mannitol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 182066-06-4 3-{2-[(2S,3R,4R,5R)-3,4-Bis-benzyloxy-2-(tert-butyl-dimethyl-silanyloxymethyl)-5-hydroxy-piperidin-1-yl]-ethyl}-indole-1-carboxylic acid tert-butyl ester 

Downstream Products

• 184781-26-8 3-{2-[(2S,3R,4R,5S)-5-Amino-3,4-bis-benzyloxy-2-(tert-butyl-dimethyl-silanyloxymethyl)-piperidin-1-yl]-ethyl}-indole-1-carboxylic acid tert-butyl ester 
• 182066-25-7 3-{2-[(2S,3R,4R,5S)-3,4-Bis-benzyloxy-5-(6-tert-butoxycarbonylamino-hexylamino)-2-(tert-butyl-dimethyl-silanyloxymethyl)-piperidin-1-yl]-ethyl}-indole-1-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

Design, synthesis and binding affinities of novel non-peptide mimics of somatostatin/Sandostatin

Based on molecular modelling studies of Sandostatin, sugar-based derivatives I-VI were prepared as potential non-peptide mimics of somatostatin/Sandostatin. These compounds displaced 3-[125I]-Tyr11-SRIF-14 from the somatostatin receptor on membranes of rat cerebral cortex with IC50 values between 10 and 15 μM.