18207-71-1 Usage
Uses
Used in Pharmaceutical Research:
10-hydroxy-9-methoxy-5,6-dihydro[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolin-7-ium is used as a research compound for exploring its pharmacological properties and potential therapeutic applications in medicinal chemistry. Its unique structure and functional groups may contribute to novel drug development and the discovery of new treatment options.
Used in Drug Discovery:
In the field of drug discovery, 10-hydroxy-9-methoxy-5,6-dihydro[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolin-7-ium is utilized as a starting point for the synthesis of new compounds with potential therapeutic effects. Its dihydro and dioxolo ring systems, along with hydroxy and methoxy groups, provide a foundation for chemical modifications and the development of more effective and targeted drugs.
Used in Medicinal Chemistry:
10-hydroxy-9-methoxy-5,6-dihydro[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolin-7-ium is employed as a key intermediate in the synthesis of various bioactive molecules in medicinal chemistry. Its unique structural features and functional groups enable the design and synthesis of novel compounds with potential applications in treating various diseases and conditions.
Used in Chemical Synthesis:
In the realm of chemical synthesis, 10-hydroxy-9-methoxy-5,6-dihydro[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolin-7-ium serves as a versatile building block for the creation of diverse chemical entities. Its dihydro and dioxolo ring systems, along with hydroxy and methoxy functional groups, offer opportunities for further functionalization and the development of new chemical compounds with various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 18207-71-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,2,0 and 7 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 18207-71:
(7*1)+(6*8)+(5*2)+(4*0)+(3*7)+(2*7)+(1*1)=101
101 % 10 = 1
So 18207-71-1 is a valid CAS Registry Number.
18207-71-1Relevant academic research and scientific papers
Lo, Sheng-Nan,Shen, Chien-Chang,Chang, Chia-Yu,Tsai, Keng-Chang,Huang, Chiung-Chiao,Wu, Tian-Shung,Ueng, Yune-Fang
, p. 1100 - 1107 (2015)
The protoberberine alkaloid berberine carries methylenedioxy moiety and exerts a variety of pharmacological effects, such as antiinflammation and lipid-lowering effects. Berberine causes potent CYP1B1 inhibition, whereas CYP1A2 shows resistance to the inh
Method for synthesizing benzophenanthridine and protoberberine alkaloids through modular diversity regulation and control
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Paragraph 0391-0396, (2021/05/29)
The invention discloses a method for synthesizing benzophenanthridine and protoberberine alkaloids through modular diversity regulation and control. The method comprises the following steps: improving a substituent group of a high-iodine salt leaving group, generating pyridine alkyne under the action of relatively mild potassium tert-butoxide, and carrying out [4 + 2] cycloaddition reaction on the pyridine alkyne and diene to obtain polysubstituted isoquinoline ring precursor compounds. Ring opening and aromatization of the isoquinoline ring precursor are realized by developing a novel iridium-catalyzed cross-coupling method, polysubstituted isoquinoline ring compounds with connecting capacity are efficiently synthesized, and then the polysubstituted isoquinoline ring compounds are coupled with a high-activity polysubstituted cyclic boric acid to obtain 3-aryl isoquinoline high-grade intermediates. Through application of two different chemical principles, regulation and control of the 3-aryl isoquinoline high-grade intermediates are realized, and benzophenanthridine and protoberberine alkaloids are modularly, diversely and efficiently synthesized.
