182072-56-6

Upstream product

• 182072-55-5 1,2-O-benzylidene-9,10-O-isopropylidene-4,20-dihydro-4α,20-dihydroxy-20-O-terbutyldimethylsilyl-5-O-mesyl taxicine I 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 182208-88-4 1,2-O-benzylidene-9,10-O-isopropylidene-4,20-dihydro-4α,20-dihydroxy-20-O-terbutyldimethylsilyl taxicine I 
• 182072-54-4 1,2-O-benzylidene-9,10-O-isopropylidene-4,20-dihydro-4α,20-dihydroxy taxicine I 
• 182072-53-3 1,2-O-benzylidene-9,10-O-isopropylidene taxicine I 
• 14550-93-7 5-O-cinnamoyl-9,10-isopropylidenetaxicine I 

Downstream Products

• 196404-39-4 2,9,10,13-tetradesacetyl-1,2-O-benzylidene-7-desacetoxy-9,10-O-isopropylidene-13-oxo baccatine IV 
• 196404-37-2 7-desacetoxy-9,10,13-tridesacetyl-9,10-O-isopropylidene baccatine VI 
• 196404-40-7 7-desacetoxy-9,10,13-tridesacetyl-9,10-O-isopropylidene-13-oxo baccatine VI 
• 196404-36-1 2,9,10,13-tetradesacetyl-1,2-O-benzylidene-7-desacetoxy-9,10-O-isopropylidene baccatine IV 

Relevant academic research and scientific papers

Taxoids: 7-Deoxy-10-acetyldocetaxel and new analogs prepared from the yew tree alkaloids

Three new 7-deoxydocetaxel derivatives have been prepared from natural taxine B and isotaxine B: the first one, 2-debenzoyl-9-dihydro-1,2-O-benzylidine-9,10-O-isopropylidene-7-deoxydocetaxel has a slight cytotoxicity and a weak microtubule disassembly inhibitory activity; the other two derivatives, 9-dihydro-9,10-O-isopropylidene-7-deoxydocetaxel and 7-deoxy-10-acetyldocetaxel are cytotoxic and reveal a good microtubule disassembly inhibitory activity.