18212-81-2

Usage

Type

Chemical compound

Usage

Synthesis of pharmaceuticals and organic products

Derivative of

1,3-propanediol

Functional groups

Hydroxyl and benzylideneamino

Role

Chiral building block in medication production

Use

Precursor in the development of other chemicals

Importance

Unique structure and functional properties valuable in pharmaceutical and chemical industries

Upstream product

• 90-02-8 salicylaldehyde 
• 77-86-1 2-amino-2-hydroxymethyl-1,3-propanediol 
• 89-95-2 2-methyl-benzyl alcohol 
• 7332-39-0 2,2,2-tris(hydroxymethyl)ethylamine 

Downstream Products

• 748107-01-9 ZnCl(2-[2-(oxybenzylidene)-amino]-2-hydroxymethylpropane-1,3-diol) 
• 949021-64-1 [Tb₄(2-((2-hydroxy-benzylidene)-amino)-2-hydroxymethyl-propane-1,3-diol(-2H))2(C₆H₄OHCHNC(CH₂OH)4)2(acetate)8*Et₂O 
• 211056-78-9 2-(2-hydroxy-benzylamino)-2-hydroxymethyl-propane-1,3-diol 

Relevant academic research and scientific papers

Zig-zag [MnIII4] clusters from polydentate Schiff base ligands

Reactions of Schiff base ligands, OH-C6H4-CHNC(R) (CH2OH)2 (R = CH3, H3L1; R = C2H5, H3L2; R = CH 2OH, H3L3

3D supramolecular networks based on hydroxyl-rich Schiff-base copper(II) complexes

Reactions of the Schiff base ligand OH-C6H4-CH[dbnd]NC(CH2OH)3 (H4L) with copper(II) salts in various reaction media afforded complexes [Cu4(H2L)4]·MeOH (1·MeOH), [Cu

Facile synthesis of a water-soluble fluorescence sensor for Al3 + in aqueous solution and on paper substrate

In this study, a facile water-soluble fluorescence sensor 2-((2-hydroxybenzylidene)-amino)-2-(hydroxymethyl)propane-1,3-diol (ST) was synthesized via one-step reaction, and its fluorescence sensing performance for Al3 + both in aqueous solution

Four-, five- and six-coordinated ZnII complexes of OH-containing ligands: Syntheses, structure and reactivity

Four-, five- and six-coordinated complexes of ZnII with OHrich molecules possessing an ONO binding core were synthesized, characterized and their structures were established by single-crystal X-ray diffraction. The corresponding metal ion geometries were found to be distorted tetrahedral, square pyramidal and octahedral, respectively. The complexes exhibit interesting lattice structures such as layered and corrugated sheets owing to the presence of a number of weak intermolecular interactions. The five-coordinated, water-bound ZnII complex was studied because of its putative hydrolysis property towards p-nitrophenyl acetate. Wiley-VCH Verlag GmbH, 69451 Weinheim, Germany, 2002.

Structurally Characterized Zn2+ Selective Ratiometric Fluorescence Probe in 100 % Water for HeLa Cell Imaging: Experimental and Computational Studies

Fluorescence recognition of Zn2+ in 100 % aqueous medium using 2-((1, 3 dihydroxy-2-(hydroxymethyl)propan-2 ylimino) methyl) phenol (SALTM) as ratiometric probe is reported. Moreover, SALTM can discriminate Zn2+ from Cd2+

Imine or Enamine? Insights and Predictive Guidelines from the Electronic Effect of Substituents in H-Bonded Salicylimines

Imine and enamine bonds decorate the skeleton of numerous reagents, catalysts, and organic materials. However, it is difficult to isolate at will a single tautomer, as dynamic equilibria occur easily, even in the solid state, and are sensitive to electronic and steric effect, including π-conjugation and H-bonding. Here, using as model Schiff bases generated from salicylaldehydes and TRIS in a set of linear free energy relationships (LFER), we disclose how the formation of either imines or enamines can be controlled and provide a comprehensive framework that captures the structural underpinning of this prediction. This work highlights the potentiality of tailor-made designs en route to compounds with desirable functionality.

Highly active dinuclear cobalt complexes for solvent-free cycloaddition of CO2 to epoxides at ambient pressure

Dinuclear Co-based catalysts are used for the coupling reaction of epoxides and CO2 in the presence of a cocatalyst. The easily recyclable catalysts efficiently complete the coupling of CO2 with various epoxides into industrially imp

ONO-type Schiff base palladium (II) complex containing multiple coordination sites and preparation method and application thereof

The invention discloses an ONO-type Schiff base palladium (II) complex containing multiple coordination sites and a preparation method and application thereof. The molecular formula of the complex is[Pd(PPh3)(C11H15NO4)], wherein PPh3 refers to triphenylp

Tetracopper complexes with two-mode cubane-like Cu4O4 core from similar hydroxyl-rich salicylaldehyde Schiff bases: Structure and magnetic properties

The reaction of water-soluble hydroxyl-rich salicylaldehyde Schiff base ligands with the metal salt Cu(OAc)2·H2O affords three novel tetracopper complexes via solvothermal method: [Cu4(H2L1)4]·CH

Synthesis, characterization and biological studies of diorganotin(IV) complexes with tris[(hydroxymethyl)aminomethane] Schiff bases

Several Schiff base ligands derived from tris(hydroxymethyl)aminomethane were synthesized and a series of diorganotin(IV) complexes were obtained from the reaction of diorganotin dichlorides or oxides with Schiff base ligands. The ligands and complexes ha