18212-81-2

Basic information

• Product Name: 2-(Hydroxymethyl)-2-(2-hydroxybenzylideneamino)-1,3-propanediol
• Synonyms: Salicylaldehyde-tris Schiff base;2-((2-HYDROXY-BENZYLIDENE)-AMINO)-2-HYDROXYMETHYL-PROPANE-1,3-DIOL;2-(Hydroxymethyl)-2-(2-hydroxybenzylideneamino)-1,3-propanediol;2-(Hydroxymethyl)-2-(salicylideneamino)-1,3-propanediol;2-(Hydroxymethyl)-2-[[(2-hydroxyphenyl)methylene]amino]-1,3-propanediol;Salicylaldehyde trisbuffer;Salicylaldehyde-tris buffer Schiff base
• CAS NO: 18212-81-2
• Molecular Formula: C₁₁H₁₅NO₄
• Molecular Weight: 225.24
• Mol File: 18212-81-2.mol
• Article Data: 15

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(Hydroxymethyl)-2-(2-hydroxybenzylideneamino)-1,3-propanediol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Hydroxymethyl)-2-(2-hydroxybenzylideneamino)-1,3-propanediol(18212-81-2)
• EPA Substance Registry System: 2-(Hydroxymethyl)-2-(2-hydroxybenzylideneamino)-1,3-propanediol(18212-81-2)

Safety Data

• Hazardous Substances Data: 18212-81-2(Hazardous Substances Data)

Usage

Type

Chemical compound

Usage

Synthesis of pharmaceuticals and organic products

Derivative of

1,3-propanediol

Functional groups

Hydroxyl and benzylideneamino

Role

Chiral building block in medication production

Use

Precursor in the development of other chemicals

Importance

Unique structure and functional properties valuable in pharmaceutical and chemical industries

Upstream product

• 90-02-8 salicylaldehyde 
• 77-86-1 2-amino-2-hydroxymethyl-1,3-propanediol 
• 89-95-2 2-methyl-benzyl alcohol 
• 7332-39-0 2,2,2-tris(hydroxymethyl)ethylamine 

Downstream Products

• 211056-78-9 2-(2-hydroxy-benzylamino)-2-hydroxymethyl-propane-1,3-diol 
• 748107-01-9 ZnCl(2-[2-(oxybenzylidene)-amino]-2-hydroxymethylpropane-1,3-diol) 
• 949021-64-1 [Tb₄(2-((2-hydroxy-benzylidene)-amino)-2-hydroxymethyl-propane-1,3-diol(-2H))2(C₆H₄OHCHNC(CH₂OH)4)2(acetate)8*Et₂O 

Relevant articles and documents

Zig-zag [MnIII4] clusters from polydentate Schiff base ligands

Reactions of Schiff base ligands, OH-C6H4-CHNC(R) (CH2OH)2 (R = CH3, H3L1; R = C2H5, H3L2; R = CH 2OH, H3L3

Facile synthesis of a water-soluble fluorescence sensor for Al3 + in aqueous solution and on paper substrate

In this study, a facile water-soluble fluorescence sensor 2-((2-hydroxybenzylidene)-amino)-2-(hydroxymethyl)propane-1,3-diol (ST) was synthesized via one-step reaction, and its fluorescence sensing performance for Al3 + both in aqueous solution

Structurally Characterized Zn2+ Selective Ratiometric Fluorescence Probe in 100 % Water for HeLa Cell Imaging: Experimental and Computational Studies

Fluorescence recognition of Zn2+ in 100 % aqueous medium using 2-((1, 3 dihydroxy-2-(hydroxymethyl)propan-2 ylimino) methyl) phenol (SALTM) as ratiometric probe is reported. Moreover, SALTM can discriminate Zn2+ from Cd2+

Highly active dinuclear cobalt complexes for solvent-free cycloaddition of CO2 to epoxides at ambient pressure

Dinuclear Co-based catalysts are used for the coupling reaction of epoxides and CO2 in the presence of a cocatalyst. The easily recyclable catalysts efficiently complete the coupling of CO2 with various epoxides into industrially imp