182122-17-4Relevant academic research and scientific papers
Traceless Photolabile Linker Expedites the Chemical Synthesis of Complex Oligosaccharides by Automated Glycan Assembly
Le Mai Hoang, Kim,Pardo-Vargas, Alonso,Zhu, Yuntao,Yu, Yang,Loria, Mirco,Delbianco, Martina,Seeberger, Peter H.
supporting information, p. 9079 - 9086 (2019/06/13)
Automated glycan assembly (AGA) aims at accelerating access to synthetic oligosaccharides to meet the demand for defined glycans as tools for molecular glycobiology. The linkers used to connect the growing glycan chain to the solid support play a pivotal
Protection and labelling of thymidine by a fluorescent photolabile group
Muller, Caroline,Even, Pascale,Viriot, Marie-Laure,Carre, Marie-Christiane
, p. 3735 - 3741 (2007/10/03)
A fluorescent photolabile group including coumarin and MeNPOC moieties was synthesized to protect 5′-OH terminal function of thymidine (T). Its photochemical and photophysical properties were studied, in particular the photocleavage (photodeprotection under a 365-nm irradiation) is only lowered by a factor of two by addition of the fluorophore. Fluorescence properties of the coumarin probe are not changed upon irradiation, which is satisfactory for the application required, i.e., in situ synthesis of DNA microarrays.
