18213-75-7

Usage

Uses

Used in Pharmaceutical Industry:
5-Amino-1-methylpyrazole-4-carboxamide is used as an intermediate in the synthesis of pharmaceuticals for its potential applications in the development of drugs. Its pharmacological properties, such as antimicrobial and anticancer activities, make it a valuable compound in the creation of new medications.
Used in Chemical Industry:
5-Amino-1-methylpyrazole-4-carboxamide is used as a building block for the synthesis of other important compounds in the chemical industry. Its versatile chemical structure allows it to be incorporated into a wide range of organic compounds, contributing to the development of various chemical products.
Used in Antimicrobial Applications:
5-Amino-1-methylpyrazole-4-carboxamide is used as an antimicrobial agent due to its ability to inhibit the growth of certain microorganisms. This property makes it a potential candidate for the development of new antibiotics and other antimicrobial drugs to combat resistant bacterial strains.
Used in Anticancer Applications:
5-Amino-1-methylpyrazole-4-carboxamide has been studied for its anticancer activities, making it a potential candidate for the development of new cancer treatments. Its ability to target and inhibit the growth of cancer cells could lead to the creation of novel therapeutic agents for various types of cancer.

InChI:InChI=1/C5H8N4O/c1-9-4(6)3(2-8-9)5(7)10/h2H,6H2,1H3,(H2,7,10)

Upstream product

• 5334-41-8 5-amino-4-cyano-1-methylpyrazole 
• 37858-68-7 α-Cyano-β-dimethylaminoacrylamide 
• 302-15-8 methylhydrazine sulfuric acid 

Downstream Products

• 5334-27-0 1-methyl-6-thioxo-1,5,6,7-tetrahydro-pyrazolo[3,4-d]pyrimidin-4-one 
• 5401-15-0 1-Methyl-1H-pyrazolo<3,4-d>pyrimidine-4,6(5H,7H)-dione 
• 36274-16-5 6-phenyl-1-methyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one 
• 139954-48-6 6-(4-methylphenyl)-1-methyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one 
• 57121-52-5 1,6-dimethyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one 
• 5334-54-3 1,5-dimethylallopurinol 
• 5417-83-4 1-methyl-6-(methylsulfanyl)-1H,4H,5H-pyrazolo[3,4-d]pyrimidin-4-one 
• 1361960-65-7 6-(difluoro-(4-fluorophenyl)methyl)-1-methyl-N-(5-methyl-1H-pyrazol-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 
• 1361961-28-5 6-(difluoro-(4-fluorophenyl)methyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-ol 
• 931075-55-7 6-(chloromethyl)-1-methyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one 
• 98550-75-5 4-chloro-1,6-dimethyl-1H-pyrazolo[3,4-d]pyrimidine 

Relevant academic research and scientific papers

COMBINATION THERAPY FOR TREATING MPS1

The application is directed to compounds of formula (I) and their salts and solvates, wherein B, R1, R2, R3, R3', R4, R4', and R5 are as set forth in the specification, as well as to methods for their preparation, pharmaceutical compositions comprising the same, and use thereof for the treatment and/or prevention of, e.g., MPS1, optionally in combination with α-L-iduronidase or an analog or variant thereof, e.g., laronidase.

ANTIVIRAL PYRIMIDINES

Disclosed herein are novel compounds comprising substituted pyrimidines, pyrazolopyrimtdines, and imidazolopyrimidines, the syntheses thereof, and compositions thereof, including pharmaceutical compositions, comprising the novel pyrimidines, pyrazolopyrimtdines, imidazolpyrimidines and related compounds. Such compounds function to inhibit entry of viruses of the Flaviviridae family, including Hepatitis C virus (HCV), into cells that are susceptible to virus infection. These compounds are useful for the treatment, therapy and/or prophylaxis of viral diseases and infection, including HCV infection.

PYRAZOLOPYRIMIDINE PI3K INHIBITOR COMPOUNDS AND METHODS OF USE

Compounds of Formula I, and including stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting lipid kinases including p110 alpha and other isoforms of PI3K, and for treating disorders such as cancer mediated by lipid kinases. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed. [Fomula I]

Pyrazolo[3,4-d]pyrimidine compounds and their use as modulators of protein kinase

The invention relates to pyrazolo[3,4-d]pyrimidine compounds of formual I and its salts wherein the substitents are as defined in the specification, their use for the treatment of protein kinase modulation responsive diseases or in the manufacture of phar