36274-16-5

Basic information

• Product Name: 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1,5-dihydro-1-methyl-6-phenyl-
• CAS NO: 36274-16-5
• Molecular Formula: C12H10N4O
• Molecular Weight: 226.238
• Mol File: 36274-16-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1,5-dihydro-1-methyl-6-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1,5-dihydro-1-methyl-6-phenyl-(36274-16-5)
• EPA Substance Registry System: 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1,5-dihydro-1-methyl-6-phenyl-(36274-16-5)

Safety Data

• Hazardous Substances Data: 36274-16-5(Hazardous Substances Data)

Upstream product

• 5334-41-8 5-amino-4-cyano-1-methylpyrazole 
• 100-52-7 benzaldehyde 
• 18213-75-7 5-amino-1-methyl-1H-pyrazole-4-carboxylic acid amide 
• 65-85-0 benzoic acid 
• 538-51-2 benzylidene phenylamine 
• 93-58-3 benzoic acid methyl ester 

Relevant articles and documents

Method for preparing medical intermediate 1H - pyrazolo [3, 4 - d] pyrimidine -4 (5H) - ketone

The invention relates to the field of pharmaceutical chemicals, and particularly discloses a preparation of a medical intermediate 1. H- Pyrazolo [3, 4 -]d] Pyrimidin -4 (5)HTo the method for - ketone, aromatic aldehyde and 5 - amino -4 -cyanopyrazole der

STUDIES ON PYRAZOLOPYRIMIDINE DERIVATIVES. XVIII. FACILE PREPARATION OF 1H-PYRAZOLOPYRIMIDIN-4(5H)-ONES

Reaction of 5-amino-1-phenyl-1H-pyrazole-4-carboxamide (4) with the esters (3a-h) in the presence of sodium ethoxide in ethanol gave 1-phenyl-1H-pyrazolopyrimidin-4(5H)-one (1a) and its 6-substituted derivatives (1b-h).Similar treatment of 5-amino-1-methyl-1H-pyrazole-4-carboxamide (5) with 3a-h gave the 1-methyl-1H-pyrazolopyrimidin-4(5H)-ones (2a-h).