182137-07-1Relevant academic research and scientific papers
Profiling structural diversity and activity of 2-alkyl-4(1H)-quinoloneN-oxides ofPseudomonasandBurkholderia
B?ttcher, Thomas,Dieterich, Cora Lisbeth,Prothiwa, Michaela,Szamosvári, Dávid
, p. 6328 - 6331 (2020)
We synthesized all major saturated and unsaturated 2-alkyl-4(1H)-quinoloneN-oxides ofPseudomonasandBurkholderia, quantified their native production levels and characterized their antibiotic activities against competingStaphylococcus aureus. We demonstrate that quinolone core methylation and position of unsaturation in the alkyl-chain dictate antibiotic potency which supports the proposed mechanism of action.
New insecticidal 4-acetoxy-2-alkenylquinolines
Minowa, Nobuto,Imamura, Kei-Ichi,Machinami, Tomoya,Shibahara, Seiji
, p. 1510 - 1512 (2007/10/03)
4-Acetoxy-2-alkenylquinolines, the analogs of quinolinol antibiotic SF2420B (1), were synthesized and their insecticidal activities were evaluated.
