18215-76-4

Upstream product

• 10297-06-0 1-chloro-5-hexyne 
• 906549-84-6 1-bromo-6-chlorohex-1-yne 
• 100-52-7 benzaldehyde 
• 945228-50-2 1,6-dichloro-hex-1-yne 
• 6940-78-9 4-chlorobutyl bromide 
• 4187-87-5 1-Phenyl-2-propyn-1-ol 

Downstream Products

• 1374748-10-3 C₁₇H₂₄ClO₄P 
• 1374748-19-2 1-(7-chloro-1-phenylhepta-1,2-dien-3-yl)-2,3,4,5,6-pentafluorobenzene 
• 1374748-28-3 1-(7-chloro-1-phenylhepta-1,2-dien-1-yl)-2,3,4,5,6-pentafluorobenzene 

Relevant academic research and scientific papers

Selective lithiation of 1,6-dihalohex-1-enes and 1,6-dihalohex-1-ynes

The lithiation of 1-choro- and 1-bromo-6-chlorohex-1-yne (2, 3) with lithium naphthalene in the presence of benzaldehyde in THF at -78 °C leads after hydrolysis with water to the corresponding chloroalkynol (5) resulting from a regioselective lithiation a

A concise access to (polyfluoroaryl)allenes by Cu-catalyzed direct coupling with propargyl phosphates

A copper-based catalyst system for the direct coupling of polyfluoroarenes with propargyl phosphates has been developed. The catalysis can provide a rapid and concise access to (polyfluoroaryl)allenes, which can be important building blocks for the synthesis of fluorinated functional materials.