182155-39-1

Upstream product

• 17599-61-0 N-benzylidene-1,1,1-trimethylsilanamine 
• 182155-26-6 (S)-1-(tert-Butyl-dimethyl-silanyl)-4-phenyl-azetidine-2,3-dione 
• 182155-22-2 (3R,4S)-1-(tert-Butyl-dimethyl-silanyl)-3-(1-methoxy-1-methyl-ethoxy)-4-phenyl-azetidin-2-one 
• 182155-28-8 (3R,4S)-1-(tert-Butyl-dimethyl-silanyl)-3-hydroxy-3-methyl-4-phenyl-azetidin-2-one 
• 182155-24-4 (3R,4S)-1-(tert-Butyl-dimethyl-silanyl)-3-hydroxy-4-phenyl-azetidin-2-one 
• 160535-69-3 (3R-cis)-3-(1-methoxy-1-methylethoxy)-4-phenyl-2-azetidinone 
• 132127-34-5 (3R,4S)-3-hydroxy-4-phenylazetidin-2-one 
• 994-30-9 triethylsilyl chloride 
• 182155-36-8 (3R,4S)-3-hydroxy-3-methyl-4-phenyl-β-lactam 
• 24424-99-5 di-tert-butyl dicarbonate 
• 182155-37-9 (3R,4S)-3-[(triethylsilyl)oxy]-4-(phenyl)-3-methyl-azetidinone 

Downstream Products

• 630127-46-7 C₅₉H₈₃NO₁₇Si₂ 

Relevant academic research and scientific papers

Synthesis and Biological Evaluation of 2′-Taxoids Derived from Baccatin III and 14β-OH-Baccatin III 1,14-Carbonate

A series of 2′-methyl taxoids were synthesized and essayed for growth inhibition experiments conducted in human ovarian cancer cell line A2780wt and its counterparts A2780cis, A2780tax, and A2780adr, resistant to cisplatin, paclitaxel, and doxorubicin, re

Diastereoselective addition of grignard reagents to azetidine-23-dione: Synthesis of novel taxol analogues

Synthesis and cytotoxicity properties of novel C-2' analogues of paclitaxel are described. The analogues were synthesized using Holton's β-lactam approach to append the side chain on baccatin III. The key intermediate to the synthesis of novel analogues w