182181-42-6

Basic information

• Product Name: 2-Chloromethyl-8-methyl-imidazo[1,2-a]pyridine
• Synonyms: Imidazo[1,2-a]pyridine, 2-(chloromethyl)-8-methyl- (9CI);2-(chloromethyl)-8-methylimidazo[1,2-a]pyridine(SALTDATA: HCl 0.87H2O);2-(chloromethyl)-8-methylimidazo[1,2-a]pyridine HCl 0.87H2O;IMidazo[1,2-a]pyridine, 2-(chloroMethyl)-8-Methyl-
• CAS NO: 182181-42-6
• Molecular Formula: C₉H₉ClN₂
• Molecular Weight: 180.63416
• Product Categories: HALOMETYL
• Mol File: 182181-42-6.mol

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2-Chloromethyl-8-methyl-imidazo[1,2-a]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloromethyl-8-methyl-imidazo[1,2-a]pyridine(182181-42-6)
• EPA Substance Registry System: 2-Chloromethyl-8-methyl-imidazo[1,2-a]pyridine(182181-42-6)

Safety Data

• Hazardous Substances Data: 182181-42-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-Chloromethyl-8-methyl-imidazo[1,2-a]pyridine is used as a chemical intermediate in the synthesis of various pharmaceuticals. Its unique chemical structure allows it to be incorporated into a wide range of drug molecules, making it a valuable component in the development of new medications.
Used in Agrochemical Industry:
2-Chloromethyl-8-methyl-imidazo[1,2-a]pyridine is also used as a chemical intermediate in the synthesis of agrochemicals. Its ability to be incorporated into various chemical structures makes it a useful component in the development of pesticides and other agricultural chemicals.

Upstream product

• 1603-40-3 3-methylpyridin-2-ylamine 
• 534-07-6 1,3-Dichloroacetone 

Relevant articles and documents

TRIAZOLO- AND PYRAZOLOQUINAZOLINE DERIVATIVES AS PDE10A ENZYME INHIBITOR

The invention relates to compounds of the formula (I) and their use as pharmaceutical ingredients, in particular for the treatment of CNS related diseases.

HETEROAROMATIC PHENYLIMIDAZOLE DERIVATIVES AS PDE10A ENZYME INHIBITORS

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NOVEL PHENYLIMIDAZOLE DERIVATIVES AS PDE10A ENZYME INHIBITORS

This invention is directed to compounds, which are PDE10A enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The present invention also provides processes for the preparation of the compounds of formula I. The present invention further provides a method of treating a subject suffering from a neurodegenerative disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention also provides a method of treating a subject suffering from a drug addiction comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention further provides a method of treating a subject suffering from a psychiatric disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I.

NOVEL PHENYLIMIDAZOLE DERIVATIVES AS PDE10A ENZYME INHIBITORS

This invention is directed to compounds, which are PDE10A enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective, amount of a compound of the invention and a pharmaceutically acceptable carrier. The present invention also provides processes for the preparation of the compounds of formula (I). The present invention further provides a method of treating a subject suffering from a neurodegenerative disorder comprising administering to the subject a therapeutically effective amount of a compound of formula (I). The present invention also provides a method of treating a subject suffering from a drug addiction comprising administering to the subject a therapeutically effective amount of a compound of formula (I). The present invention further provides a method of treating a subject suffering from a psychiatric disorder comprising administering to the subject a therapeutically effective amount of a compound of formula (I).

NOVEL ALKYNYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS

The present invention relates to novel compounds of formula (I) wherein W, n, X and W’ are defined in the description; invention compounds are modulators of metabotropic glutamate receptors - subtype 5 (“mGluR5”) which are useful for the treatment of central nervous system disorders as well as other disorders modulated by mGluR5 receptors.

MALONONITRILE COMPOUND AS PESTICIDES

The present invention provides a malononitrile compound represented by the formula (I): wherein any one of X1, X2, X3 and X4 is CR100, wherein R100 is a group represented by the formula: the other three of X1, X2, X3 and X4 each represent nitrogen or CR5, provided that 1 to 3 of X1, X2, X3 and X4 represent nitrogen, and Z represents oxygen, sulfur or NR6, which has pest-controlling activity.

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The present invention relates to imidazo[1,2-a]pyridine compounds of formula (1) STR1 which are dopamine D-4 antagonists and useful as anti-psychotic agents.