182244-16-2 Usage
Uses
Used in Pharmaceutical Industry:
6-Chloro-5-isobutyl-pyrazine-2-carboxylic acid amide is used as a target for drug development due to its potential therapeutic properties and pharmacological activities.
Used in Research:
6-Chloro-5-isobutyl-pyrazine-2-carboxylic acid amide is used as a research compound for studying its potential as an antifungal and antibacterial agent, as well as its potential in the treatment of various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 182244-16-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,2,2,4 and 4 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 182244-16:
(8*1)+(7*8)+(6*2)+(5*2)+(4*4)+(3*4)+(2*1)+(1*6)=122
122 % 10 = 2
So 182244-16-2 is a valid CAS Registry Number.
182244-16-2Relevant academic research and scientific papers
Synthesis and antituberculotic activity of 5-alkyl-6-chloro-2-pyrazinecarboxamides and corresponding thioamides
Hartl, Jiri,Dolezal, Martin,Krinkova, Jana,Lycka, Antonin,Odlerova, Zelmira
, p. 1109 - 1114 (2007/10/03)
Homolytic alkylation of 6-chloro-2-pyrazinecarbonitrile by alkanoic acid and subsequent partial hydrolysis afforded 5-alkyl-6-chloro-2-pyrazinecarboxamides 1a-1e. Reaction of amides 1a-1e by Lawesson's reagent afforded corresponding thioamides 2a-2e. The structure of compounds was confirmed by elemental analysis, IR and 1H NMR spectra. The assessment of in vitro antimycobacterial activity of the compounds was carried out. The highest antituberculotic activity against Mycobacterium tuberculosis and other mycobacterial strains in this series was shown by 5-(1,1-dimethylethyl)-6-chloro-2-pyrazinecarbothioamide (2e).
