1823-21-8

Basic information

• Product Name: 2-p-Toluolsulfonylamino-2'-methoxy-benzophenon
• Synonyms: 2-p-Toluolsulfonylamino-2'-methoxy-benzophenon
• CAS NO: 1823-21-8
• Molecular Weight: 381.452
• Mol File: 1823-21-8.mol

Chemical Properties

• CAS DataBase Reference: 2-p-Toluolsulfonylamino-2'-methoxy-benzophenon(CAS DataBase Reference)
• NIST Chemistry Reference: 2-p-Toluolsulfonylamino-2'-methoxy-benzophenon(1823-21-8)
• EPA Substance Registry System: 2-p-Toluolsulfonylamino-2'-methoxy-benzophenon(1823-21-8)

Safety Data

• Hazardous Substances Data: 1823-21-8(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 133776-41-7 anthranilic acid N-methoxy-N-methylamide 
• 578-57-4 2-bromoanisole 

Relevant articles and documents

Diastereo- And Atroposelective Synthesis of Bridged Biaryls Bearing an Eight-Membered Lactone through an Organocatalytic Cascade

We present herein an unprecedented stereoselective synthesis of bridged biaryls with defined axial and central chirality from readily available starting materials. This N-heterocyclic carbene-catalyzed method proceeds through propargylic substitution of azolium enolates followed by two-directional cyclization, as supported by DFT calculation. A range of benzofuran/indole-derived bridged biaryls bearing an eight-membered lactone are accessed with uniformly high stereoselectivity (>98:2 dr, mostly >98% ee).