1823-47-8

Basic information

• Product Name: SALICYLIDENE 2-AMINOPYRIDINE
• Synonyms: 2-(Salicylideneamino)pyridine;2-[(E)-(2-Pyridinylimino)methyl]phenol;2-Pyridinamine, N-(2-hydroxybenzylidene)-;N-Pyridylsalicylideneamine;N-Salicylidene-2-aminopyridine;N-Salicylidene-2-pyridinamine;Phenol, 2-((2-pyridinylimino)methyl)-;Phenol, o-(N-2-pyridylformimidoyl)-
• CAS NO: 1823-47-8
• Molecular Formula: C₁₂H₁₀N₂O
• Molecular Weight: 198.22
• Mol File: 1823-47-8.mol

Chemical Properties

• Melting Point: 185-186 °C
• Boiling Point: 369.618 °C at 760 mmHg
• Flash Point: 177.339 °C
• Appearance: /
• Density: 1.13 g/cm³
• Vapor Pressure: 7.42E-06mmHg at 25°C
• Refractive Index: 1.758
• PKA: 8.51±0.35(Predicted)
• CAS DataBase Reference: SALICYLIDENE 2-AMINOPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: SALICYLIDENE 2-AMINOPYRIDINE(1823-47-8)
• EPA Substance Registry System: SALICYLIDENE 2-AMINOPYRIDINE(1823-47-8)

Safety Data

• Hazardous Substances Data: 1823-47-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
SALICYLIDENE 2-AMINOPYRIDINE is used as an intermediate for the synthesis of new drugs, leveraging its ability to form coordination complexes to enhance the properties of pharmaceutical compounds.
Used in Antimicrobial Applications:
SALICYLIDENE 2-AMINOPYRIDINE is being studied for its potential as an antimicrobial agent, with research focusing on its ability to combat various types of infections by interacting with metal ions essential for microbial growth.
Used in Anticancer Research:
SALICYLIDENE 2-AMINOPYRIDINE is used as a subject of investigation in anticancer studies, exploring its potential to target and disrupt processes within cancer cells, thereby contributing to the development of novel cancer therapies.
Used in Organic Light-Emitting Diodes (OLED) Production:
SALICYLIDENE 2-AMINOPYRIDINE is utilized in the production of OLEDs, where its fluorescent properties are harnessed to improve the efficiency and performance of these devices.
Used in Molecular Imaging Techniques:
SALICYLIDENE 2-AMINOPYRIDINE is used as a fluorescent probe in molecular imaging, allowing for the visualization and tracking of biological processes at the molecular level, which is crucial for understanding disease mechanisms and developing targeted therapies.
Used in Chemical and Biological Research:
SALICYLIDENE 2-AMINOPYRIDINE is employed as a valuable component in a wide array of chemical and biological research activities, owing to its unique structure and the diverse interactions it can engage in with other molecules and metal ions.

InChI:InChI=1/C12H10N2O/c15-11-6-2-1-5-10(11)9-14-12-7-3-4-8-13-12/h1-9H,(H,13,14)

Upstream product

• 504-29-0 2-aminopyridine 
• 90-02-8 salicylaldehyde 
• 109-09-1 2-chloropyridine 
• 110-86-1 pyridine 
• 89-95-2 2-methyl-benzyl alcohol 

Downstream Products

• 70301-52-9 2-<(o-hydroxybenzyl)amino>pyridine 
• 66386-01-4 2-(2-hydroxy-phenyl)-3-pyridin-2-yl-thiazolidin-4-one 
• 504-29-0 2-aminopyridine 
• 90-02-8 salicylaldehyde 
• 613220-92-1 RuCl(1,10-phenanthroline)(triphenylphosphine)(C₆H₄(O)CHNC₅H₄N) 
• 613220-86-3 RuCl(carbon monosulfide)(pyridine)(triphenylphosphine)(C₆H₄(O)CHNC₅H₄N) 
• 500552-61-4 [RuCl(CO)(C₅H₅N)(P(C₆H₅)3)(C₆H₄(O)CHNC₅H₄N)] 
• 500552-67-0 [RuCl(CO)(C₄H₉NO)(P(C₆H₅)3)(C₆H₄(O)CHNC₅H₄N)] 
• 500552-64-7 [RuCl(CO)(C₅H₁₁N)(P(C₆H₅)3)(C₆H₄(O)CHNC₅H₄N)] 
• 14523-25-2 {Cusal₂} 
• 944284-72-4 N-2-pyridyl(salicylideneimine), sodium salt 
• 950913-36-7 CrCl(OC₆H₄CHNC₅H₄N)(OH)(H₂O)2*H₂O 

Relevant articles and documents

Integration of an aminopyridine derived cobalt based homogenous cocatalyst with a composite photocatalyst to promote H2evolution from water

Inexpensive cocatalysts are promising materials to improve the performance of photocatalytic systems. However, a cocatalyst can be anchored onto a photosensitizer in certain amount and further loading can hinder the visible light by blocking the active si

Linear trinuclear cobalt(ii) single molecule magnet

The introduction of NaBPh4 into a methanolic solution of CoCl2·6H2O and 2-[(pyridine-2-ylimine)-methyl]phenol (Hpymp) afforded {[CoII3(pymp)4(MeOH)2][BPh4]2

Intramolecular hydrogen bonding and tautomerism in Schiff bases. Structure of N-(2-pyridil)-2-oxo-1-naphthylidenemethylamine

N-(2-pyridil)-salicylidene (1) and N-(2-pyridil)-2-oxo-1-naphthylidene- methylamine (2) were studied by elemental analysis, IR, 1H NMR and UV- visible techniques and the structure of compound (2) was examined crystallographically. The UV-visible spectra of 2-hydroxy Schiff bases are investigated in different solvents, acidic and basic media. Compound (2) is in tautomeric equilibrium (phenol-imine, O-H···N ? keto-amine, O···H-N forms) in polar and non-polar solvents. These tautomers are not observed in polar and non-polar solvents for (1) as also supported by 1H NMR and UV- visible data. The keto-amine form of compound (2) was observed in basic solutions of DMSO, ethanol, chloroform, benzene, cyclohexane and in acidic solutions of chloroform and benzene, but not in acidic solutions of DMSO and ethanol. On the contrary, this form for compound (1) was not observed in the same solutions. The asymmetric unit of compound (2) contains two independent molecules of (C16H12N2O) which constitute a tautomeric pair. The observed differences in the related C = N (1.317(4) and 1.330(4) A?) and C-O (1.279(4) and 1.263(4) A?) bond lengths in the two crystallographically independent molecules indicate that the phenol-imine and the keto-amine forms coexist in the solid state. Intramolecular hydrogen bond lengths (O-H···N) are 2.586(4) A? and 2.518(4) A? for the two individual tautomers. It crystallizes in the monoclinic space group P21/n with a = 5.837(2), b = 17.476(2), c = 24.295(3) A?, β = 91.95(4)°, V = 2476.9(6) A?3, Z = 4 and D(x) = 1.3315 g cm-3. (C) 2000 Elsevier Science B.V.

The structure and tautomeric properties of 2-(3-pyridylmethyliminomethyl)phenol

The structure and properties of 2-(3-pyridylmethyliminomethyl)phenol have been determined by X-ray crystallography, NMr, UV, IR spectroscopy and compared with the characteristics of the Schiff bases derived from salicylaldehyde and aminopyridines.Crystal

Spontaneous resolution of a Δ/Λ-chiral-at-metal pseudo-tetrahedral Schiff-base zinc complex to a racemic conglomerate with C-H?O organized 41- and 43-helices

The Schiff-base ligand N-2-(pyridyl)salicylaldimine (HL) reacts with zinc(ii) acetate or nitrate to obtain the enantiomorphous chiral-at-metal compound Δ/Λ-bis[N-2-(pyridyl)salicylaldiminato-κ2N,O]zinc(ii), [Zn(L)2] (1), which crysta

Structure and magnetic properties of a tetranuclear Cu(II) complex containing the 2-(pyridine-2-yliminomethyl)-phenol ligand

A tetranuclear Cu(II) complex [Cu4L4(H 2O)4](ClO4)4 has been synthesized using the terdentate Schiff base 2-(pyridine-2-yliminomethyl)-phenol (HL) (the condensation product of salicylaldehy

Synthesis, spectroscopic characterization and DNA cleavage studies of dibutyltin(IV) complexes of bidentate Schiff bases

Reactions of di-n-butyltin(IV)dichloride with sodium salts of Schiff bases in tetrahydrofuran-benzene solution in 1:1 and 1:2 stoichiometry afforded complexes of the types [(n-Bu)2Sn(sb)Cl] and [(n-Bu) 2Sn(sb)2], respectiv

Spectroscopic, thermal and antimicrobial properties of the copper(II) complex of Schiff base derived from 2-(salicylidene) aminopyridine

Schiff bases and their complex combinations with metallic ions represent a class of compounds with antimicrobial activity. A ligand was prepared by condensation of the salicylaldehyde with 2-aminopyridine obtaining 2-(salicylidene) aminopyridine (SB) with

Triorganotin(IV) derivatives of bidentate schiff bases: Synthesis and spectral studies

Reaction of tri-n-butyl tin(IV) chloride with the sodium salt of Schiff bases [salicylidene-2-aminopyridine (sapH), salicylidene-2-amino-4-picoline (sapicH), salicylidene-2-methyl-1-aminobenzene (o-smabH), salicylidene-4-methyl- 1-aminobenzene (p-smabH),

Synthesis and physicochemical characterization of some hexacoordinated tin(IV) Schiff base complexes

A freshly distilled tin(IV) tetrachloride interacted with sodium salts of Schiff bases in 1:2 molar ratios in a mixture of tetrahydrofuron (THF)-C 6 H6 produced complexes of the type [SnCl2 (sb) 2 ], [where sb =