182344-70-3

Basic information

• Product Name: TERT-BUTYL 5-BROMOINDOLE-1-CARBOXYLATE
• Synonyms: 5-BROMO-1-(TERT-BUTOXYCARBONYL)-1H-INDOLE;TERT-BUTYL 5-BROMO-1H-INDOLE-1-CARBOXYLATE;TERT-BUTYL 5-BROMOINDOLE-1-CARBOXYLATE;N-Boc-5-bromoindole;5-Bromo-1-(t-Butoxycarbonyl)-1H-indole;1-BOC-5-bromoindole;5-Bromo-1-tert-butoxycarbonylindole
• CAS NO: 182344-70-3
• Molecular Formula: C₁₃H₁₄BrNO₂
• Molecular Weight: 296.16
• Product Categories: Halides;Pyrroles & Indoles;Indole;Pyrroles & Indoles
• Mol File: 182344-70-3.mol
• Article Data: 0

Chemical Properties

• Melting Point: 56-57 °C(lit.)
• Boiling Point: 367.9 °C at 760 mmHg
• Flash Point: 176.3 °C
• Appearance: /
• Density: 1.37 g/cm³
• Vapor Pressure: 1.33E-05mmHg at 25°C
• Refractive Index: 1.576
• Storage Temp.: Room temperature.
• CAS DataBase Reference: TERT-BUTYL 5-BROMOINDOLE-1-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: TERT-BUTYL 5-BROMOINDOLE-1-CARBOXYLATE(182344-70-3)
• EPA Substance Registry System: TERT-BUTYL 5-BROMOINDOLE-1-CARBOXYLATE(182344-70-3)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 182344-70-3(Hazardous Substances Data)

Usage

General Description

N-Boc-5-bromoindole can undergo Sonogashira coupling reaction with N,N-diisopropylprop-2-ynylamine to afford the corresponding propargylic diisopropylamine. N-Boc-5-bromoindole is formed as an intermediate during the synthesis of 2-(5-substituted-1H-indol-3-yl)-N-hydroxyacetamide derivatives.

InChI:InChI=1/C13H14BrNO2/c1-13(2,3)17-12(16)15-7-6-9-8-10(14)4-5-11(9)15/h4-8H,1-3H3

Downstream Products

• 475102-13-7 2-borono-5-bromo-1H-indole-1-carboxylic acid-1-(1,1-dimethylethyl) ester 
• 777061-36-6 1,1-dimethylethyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylate 
• 10075-50-0 5-bromo-1H-indole 
• 1007893-46-0 tert-butyl 5-(2-tert-butyl-4-methylphenoxy)indole-1-carboxylate 
• 1007893-41-5 tert-butyl 5-(2-methylphenoxy)indole-1-carboxylate 
• 1037522-51-2 tert-butyl 5-[4-(3-methylphenyl)piperazin-1-yl]-1H-indole-1-carboxylate 
• 1037522-53-4 tert-butyl 5-(benzylamino)-1H-indole-1-carboxylate 
• 1126784-57-3 5-(3-ethoxycarbonylphenyl)-indole-1-carboxylic acid tert-butyl ester 
• 129822-47-5 tert‐butyl 5‐fluoroindole‐1‐carboxylate 
• 1205744-85-9 N-Boc-5-bromo-2-(4-methoxycarbonylphenyl)indole 
• 1205744-86-0 N-Boc-5-bromo-2-(4-trifluoromethylphenyl)indole 
• 1309660-31-8 tert-butyl 5-(2-cyanopropan-2-yl)-1H-indole-1-carboxylate 
• 1315258-53-7 C₃₀H₃₀N₂O₄ 
• 1316859-68-3 tert-butyl 5-(4-nitrobenzyl)-1H-indole-1-carboxylate