182356-05-4

Basic information

• Product Name: (4S,5R)-1-[(R)-3-(4'-Bromo-biphenyl-4-yl)-4-phenyl-butyryl]-3,4-dimethyl-5-phenyl-imidazolidin-2-one
• Synonyms: (4S,5R)-1-[(R)-3-(4'-Bromo-biphenyl-4-yl)-4-phenyl-butyryl]-3,4-dimethyl-5-phenyl-imidazolidin-2-one
• CAS NO: 182356-05-4
• Molecular Weight: 567.525
• Mol File: 182356-05-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4S,5R)-1-[(R)-3-(4'-Bromo-biphenyl-4-yl)-4-phenyl-butyryl]-3,4-dimethyl-5-phenyl-imidazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4S,5R)-1-[(R)-3-(4'-Bromo-biphenyl-4-yl)-4-phenyl-butyryl]-3,4-dimethyl-5-phenyl-imidazolidin-2-one(182356-05-4)
• EPA Substance Registry System: (4S,5R)-1-[(R)-3-(4'-Bromo-biphenyl-4-yl)-4-phenyl-butyryl]-3,4-dimethyl-5-phenyl-imidazolidin-2-one(182356-05-4)

Safety Data

• Hazardous Substances Data: 182356-05-4(Hazardous Substances Data)

Upstream product

• 190729-08-9 (E)-3-(4'-Bromo-biphenyl-4-yl)-acrylic acid ethyl ester 
• 92841-65-1 (4R,5S)-1,5-dimethyl-4-phenylimidazolidin-2-one 
• 182356-04-3 (4S,5R)-1-[(E)-3-(4'-Bromo-biphenyl-4-yl)-acryloyl]-3,4-dimethyl-5-phenyl-imidazolidin-2-one 

Downstream Products

• 56073-10-0 3S-(4'-bromobiphenyl-4-yl)-1S-(4-hydroxycoumarin-3-yl)-1,2,3,4-tetrahydronaphthalene 
• 56073-10-0 3S-(4'-bromobiphenyl-4-yl)-1R-(4-hydroxycoumarin-3-yl)-1,2,3,4-tetrahydronaphthalene 
• 182356-07-6 (R)-3-(4'-Bromo-biphenyl-4-yl)-3,4-dihydro-2H-naphthalen-1-one 

Relevant articles and documents

Efficient asymmetric synthesis of the four diastereomers of diphenacoum and brodifacoum

A highly stereo- and enantio-selective approach to the four stereoisomers of the rodenticides, diphenacoum and brodifacoum, is described. The key step involves the stereospecific formation of one of the crucial bonds in the molecular backbone, and is based on asymmetric organocopper 1,4-addition to chiral imides. Intramolecular cyclization of the resulting butanoate and coupling with 4-hydroxycoumarin, afford the title compounds.