92841-65-1

Basic information

• Product Name: (4R 5S)-1 5-DIMETHYL-4-PHENYL-2-IMIDAZOLIDONE
• Synonyms: (4R,5S)-(-)-1,5-DIMETHYL-4-PHENYL-2-IMIDAZOLIDINONE;(4R 5S)-1 5-DIMETHYL-4-PHENYL-2-IMIDAZOLIDONE;(4R,5S)-1,5-DIMETHYL-4-PHENYLIMIDAZOLIDINONE;1,5-dimethyl-4-phenyl-2-imidazolidine;(4R)-4α-Phenyl-1,5α-dimethylimidazolidine-2-one;(4R,5S)-1,5-Dimethyl-4-phenylimidazolidine-2-one;[4R,5S,(-)]-1,5-Dimethyl-4-phenylimidazolidin-2-one;(4R,5S)-(-)-1,5-DiMethyl-4-phenyl-2-iMidazolidinone 97%
• CAS NO: 92841-65-1
• Molecular Formula: C₁₁H₁₄N₂O
• Molecular Weight: 190.24
• Product Categories: Chiral Building Blocks;Heterocyclic Building Blocks;Imidazolines/Imidazolidines
• Mol File: 92841-65-1.mol
• Article Data: 16

Chemical Properties

• Melting Point: 171-174 °C(lit.)
• Boiling Point: 335.9°C at 760 mmHg
• Flash Point: 156.9°C
• Appearance: /
• Density: 1.077g/cm³
• Vapor Pressure: 0.000116mmHg at 25°C
• Refractive Index: 1.532
• PKA: 13.70±0.60(Predicted)
• BRN: 3607899
• CAS DataBase Reference: (4R 5S)-1 5-DIMETHYL-4-PHENYL-2-IMIDAZOLIDONE(CAS DataBase Reference)
• NIST Chemistry Reference: (4R 5S)-1 5-DIMETHYL-4-PHENYL-2-IMIDAZOLIDONE(92841-65-1)
• EPA Substance Registry System: (4R 5S)-1 5-DIMETHYL-4-PHENYL-2-IMIDAZOLIDONE(92841-65-1)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• Hazardous Substances Data: 92841-65-1(Hazardous Substances Data)

Usage

Uses

Employed in the synthesis of optically active mono-, di-, and trihydroxy compounds.

InChI:InChI=1/C11H14N2O/c1-8-10(12-11(14)13(8)2)9-6-4-3-5-7-9/h3-8,10H,1-2H3,(H,12,14)/t8-,10-/m0/s1

Upstream product

• 197232-68-1 (4R,5S,3'R)-1,5-dimethyl-3-(2'-acetamido-3'-hydroxypropionyl)-4-phenylimidazolidin-2-one 
• 176791-98-3 (4R,5S,2'R,3'S)-1,5-dimethyl-3-(2'-acetamido-3'-acetoxybutyryl)-4-phenylimidazolidin-2-one 
• 172536-18-4 (4S,5R)-1-[4-tert-Butyl-1-((S)-1-hydroxy-ethyl)-cyclohexanecarbonyl]-3,4-dimethyl-5-phenyl-imidazolidin-2-one 
• 128863-73-0 (4R,5S)-1,5-Dimethyl-4-phenyl-3-((R)-3-phenyl-hex-5-enoyl)-imidazolidin-2-one 
• 128863-72-9 (4R,5S)-1,5-Dimethyl-3-((R)-3-methyl-hex-5-enoyl)-4-phenyl-imidazolidin-2-one 
• 67-56-1 methanol 
• 136630-07-4 (4R,5S,2'R,3'R)-3-<3-hydroxy-2-methyl-3-(4-nitrophenyl)propanoyl>-1,5-dimethyl-4-phenylimidazolidin-2-one 
• 136630-06-3 (4R,5S,2'R,3'R)-3-<3-hydroxy-2-methyl-3-(4-methoxyphenyl)propanoyl>-1,5-dimethyl-4-phenylimidazolidin-2-one 
• 136630-05-2 (4R,5S,2'R,3'R)-1,5-dimethyl-4-phenyl-3-(3'-hydroxy-2'-methyl-3'-phenylpropanoyl)imidazolidin-2-one 
• 57-13-6 urea 
• 90-81-3 ephedrine 
• 4785-79-9 1,3-dihydro-1,5-dimethyl-4-phenyl-2H-imidazol-2-one 
• 128947-02-4 (4R,5S)-1,5-dimethyl-3-[(2E)-3-phenyl-2-propenoyl]-4-phenyl-2-imidazolidinone 
• 112712-55-7 deux références XF130 et XF154 

Downstream Products

• 143359-35-7 (4S,5R)-1-(3'-phenylpropionoyl)-3,4-dimethyl-5-phenylimidazolidin-2-one 
• 317845-44-6 (4R,5R,1'S)-1,5-dimethil-3-[1-(phenylsulfonyl)-3-phenylpropyl]-4-phenylimidazolidin-2-one 
• 317845-50-4 (4R,5S,1'S)-1,5-dimethyl-3-[1-(phenylsulfonyl)-6-chlorohexyl]-4-phenylimidazolidin-2-one 
• 256382-73-7 (4R,5S)-1,5-Dimethyl-4-phenyl-3-prop-2-ynyl-imidazolidin-2-one 
• 143359-34-6 (4R,5S)-1,5-Dimethyl-3-(3-methyl-butyryl)-4-phenyl-imidazolidin-2-one 
• 128947-02-4 (4R,5S)-1,5-dimethyl-3-[(2E)-3-phenyl-2-propenoyl]-4-phenyl-2-imidazolidinone 
• 143359-25-5 (4S,5R)-(-)-(2'-chloroacetyl)-3,4-dimethyl-5-phenyl-2-imidazolidinone 
• 143359-26-6 (4S,5R)-1-Acetyl-3,4-dimethyl-5-phenyl-imidazolidin-2-one 
• 112712-55-7 deux références XF130 et XF154 
• 142061-15-2 (4R,5S)-1,5-dimethyl-4-cyclohexyl-2-imidazolidinone 
• 331283-86-4 (4R,5S)-4-cyclohexyl-1,5-dimethyl-3-(2-propenoyl)-2-imidazolidinone 
• 139962-51-9 (4R,5S)-1,5-Dimethyl-3-((E)-pent-2-enoyl)-4-phenyl-imidazolidin-2-one 
• 123483-75-0 (4S,5R)-1-benzyloxyacetyl-3,4-dimethyl-5-phenyl-imidazolidin-2-one 
• 128947-01-3 (4R,5S)-3-[(2E)-2-butenoyl]-1,5-dimethyl-4-phenyl-2-imidazolidinone 

Relevant articles and documents

Intramolecular carbolithiation of heterosubstituted alkynes: An experimental and theoretical study

A series of heterosubstitued alkynes was successfully submitted to the intramolecular carbolithiation of their triple bond. We show that the addition is stereoselective because of the control exerted by the terminal substituent X on the geometry of the transition state. A complementary DFT study suggests that the addition is anti when a strong Li-X interaction occurs.

Studies on a urea-directed Stork-Crabtree hydrogenation. Synthesis of the C1-C9 subunit of (+)-zincophorin

(Chemical Equation Presented) A detailed account on the stereoselective synthesis of the C1-C9 subunit of (+)-zincophorin is described here. This approach features the first application of a stereoselective inverse electron demand hetero-[4 + 2] cycloaddi

Microwave-assisted ring expansion of N-acetyl 3′-unsubstituted aziridine in the presence of Lewis acids

The microwave-assisted ring expansion of N-acetyl 3′-unsubstituted aziridine-2-imides and N-acetyl 3′-unsubstituted aziridine-2-esters to oxazolines is reported. The regioselectivities of the rearrangements depend upon the reaction conditions, such as the Lewis acid selected and the solvent.