1824-00-6Relevant academic research and scientific papers
Direct synthesis of 3-halo-3-arylacrylonitriles from the addition of cyanoalkynes with alkaline metal halides
Guan, Zhipeng,Liu, Zhiwen,Shi, Wei,Chen, Hao
, p. 3602 - 3606 (2017)
An efficient synthesis of 3-halo-3-arylacrylonitrile is described from the direct addition between cyanoalkynes and inorganic alkaline metal halides such as LiCl, LiBr and KI in good to satisfactory yields. No transition metal is needed for the synthesis
Gallium (iii)-catalysed bromocyanation of alkynes: Regio- and stereoselective synthesis of β-bromo-α,β-unsaturated nitriles
Murai, Masahito,Hatano, Ryo,Kitabata, Sachie,Ohe, Kouichi
supporting information; experimental part, p. 2375 - 2377 (2011/04/18)
Treatment of arylacetylenes and cyanogen bromide in ClCH2CH 2Cl with a catalytic amount of GaCl3 afforded (Z)-β-bromoacrylonitriles with high regio- and stereoselectivity.
