182416-72-4Relevant academic research and scientific papers
Cobalt-Catalyzed Stereoselective Synthesis of 2,5- trans-THF Nitrile Derivatives as a Platform for Diversification: Development and Mechanistic Studies
Ali, Sajjad,Milanezi, Henrique,Alves, Tania M. F.,Tormena, Cláudio Francisco,Ferreira, Marco A. B.
, p. 7694 - 7713 (2018/06/18)
A straightforward protocol integrating a sustainable approach for the synthesis of new 2,5-trans-THF nitrile derivatives enabling an easy diversification of its side chain scaffolds is described. The reaction tolerated different aromatic and alkyl substit
Indium-mediated regioselective allylation of terminal epoxides: A facile synthesis of bishomoallyl alcohols
Yadav,Anjaneyulu,Moinuddin Ahmed,Subba Reddy
, p. 2557 - 2559 (2007/10/03)
Allyl indium, prepared from allyl bromide and indium metal in THF, reacts with terminal epoxides at room temperature to afford the corresponding bishomoallyl alcohols in excellent yields and with good regioselectivity.
Enantioselective parallel synthesis using polymer-supported chiral Co(salen) complexes
Peukert, Stefan,Jacobsen, Eric N.
, p. 1245 - 1248 (2008/02/09)
(matrix presented) The kinetic resolution of epoxides with phenols catalyzed by a polymer-supported Co(salen) complex is applied to the first enantioselective catalytic synthesis of parallel libraries. The corresponding 1-aryloxy-2-alcohols are obtained i
Synthesis of tetrahydrofurans by the reaction of α,β-epoxy alcohol derivatives with allylsilanes
Sugita, Yoshiaki,Kimura, Yoko,Yokoe, Ichiro
, p. 5877 - 5880 (2007/10/03)
In the presence of SnCl4, α,β-epoxy alcohol derivatives easily reacted with allylsilanes to give the corresponding tetrahydrofurans in moderate yields.
Diastereoselective Rh-mediated construction of 2,3,5-trisubstituted tetrahydrofurans
Taber, Douglass F.,Song, Ying
, p. 6706 - 6712 (2007/10/03)
Dirhodium(II) carboxylate catalyzed cyclization of a series of γ-alkoxy-α-diazo esters 1 has been shown to proceed with substantial diastereoselectivity, producing the 2,3,5-trisubstituted tetrahydrofurans 2 and 3. The diastereoselectivity of the cyclizat
2,3,5-TRISUBSTITUTED TETRAHYDROFURANS BY Rh-MEDIATED CYCLISATION OF AN α-DIAZO ESTER
Taber, Douglass F.,Song, Ying
, p. 2587 - 2590 (2007/10/02)
Dirhodium(II) carboxylate catalyzed cyclization of a γ-alkoxy-α-diazo ester 1 was found to proceed with substatial diastereoselectivity, producing the 2,3,5-trisubstituted tetrahydrofurans 2a and 2b in a ratio of 4:1.
