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18246-04-3

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18246-04-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 18246-04-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,2,4 and 6 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 18246-04:
(7*1)+(6*8)+(5*2)+(4*4)+(3*6)+(2*0)+(1*4)=103
103 % 10 = 3
So 18246-04-3 is a valid CAS Registry Number.

18246-04-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name (4-chlorophenyl)-hydroxy-dimethylsilane

1.2 Other means of identification

Product number -
Other names Silanol,1-(4-chlorophenyl)-1,1-dimethyl

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:18246-04-3 SDS

18246-04-3Relevant academic research and scientific papers

Diorganotelluride-catalyzed oxidation of silanes to silanols under atmospheric oxygen

Okada, Yasunori,Oba, Makoto,Arai, Atsushi,Tanaka, Kazuhito,Nishiyama, Kozaburo,Ando, Wataru

, p. 383 - 385 (2010)

Diorganotellurides efficiently catalyze the aerobic oxidation of organosilanes under photosensitized conditions to afford the corresponding silanols in excellent yield.

Metal-free hydrogen evolution cross-coupling enabled by synergistic photoredox and polarity reversal catalysis

Cao, Jilei,Lu, Kanghui,Ma, Lishuang,Yang, Xiaona,Zhou, Rong

, p. 8988 - 8994 (2021/11/23)

A synergistic combination of photoredox and polarity reversal catalysis enabled a hydrogen evolution cross-coupling of silanes with H2O, alcohols, phenols, and silanols, which afforded the corresponding silanols, monosilyl ethers, and disilyl ethers, respectively, in moderate to excellent yields. The dehydrogenative cross-coupling of Si-H and O-H proceeded smoothly with broad substrate scope and good functional group compatibility in the presence of only an organophotocatalyst 4-CzIPN and a thiol HAT catalyst, without the requirement of any metals, external oxidants and proton reductants, which is distinct from the previously reported photocatalytic hydrogen evolution cross-coupling reactions where a proton reduction cocatalyst such as a cobalt complex is generally required. Mechanistically, a silyl cation intermediate is generated to facilitate the cross-coupling reaction, which therefore represents an unprecedented approach for the generation of silyl cationviavisible-light photoredox catalysis.

Selective Electrochemical Hydrolysis of Hydrosilanes to Silanols via Anodically Generated Silyl Cations

Liang, Hao,Wang, Lu-Jun,Ji, Yun-Xing,Wang, Han,Zhang, Bo

supporting information, p. 1839 - 1844 (2020/12/01)

The first electrochemical hydrolysis of hydrosilanes to silanols under mild and neutral reaction conditions is reported. The practical protocol employs commercially available and cheap NHPI as a hydrogen-atom transfer (HAT) mediator and operates at room temperature with high selectivity, leading to various valuable silanols in moderate to good yields. Notably, this electrochemical method exhibits a broad substrate scope and high functional-group compatibility, and it is applicable to late-stage functionalization of complex molecules. Preliminary mechanistic studies suggest that the reaction appears to proceed through a nucleophilic substitution reaction of an electrogenerated silyl cation with H2O.

Photocatalyzed cross-dehydrogenative coupling of silanes with alcohols and water

Lv, Haiping,Laishram, Ronibala Devi,Chen, Jingchao,Khan, Ruhima,Zhu, Yuanbin,Wu, Shiyuan,Zhang, Jianqiang,Liu, Xingyuan,Fan, Baomin

supporting information, p. 3660 - 3663 (2021/04/16)

An efficient method for the dehydrogenative coupling of silanes with alcohols under photocatalysis was developed. The reaction proceeded in the presence of Ru(bpy)3Cl2(0.5 mol%) under visible light irradiation in acetonitrile at room temperature. The developed methodology was also applicable for the synthesis of silanols using water as a coupling partner.

Catalytic Enantioselective Dehydrogenative Si-O Coupling to Access Chiroptical Silicon-Stereogenic Siloxanes and Alkoxysilanes

Zhu, Jiefeng,Chen, Shuyou,He, Chuan

supporting information, p. 5301 - 5307 (2021/05/04)

A rhodium-catalyzed enantioselective construction of triorgano-substituted silicon-stereogenic siloxanes and alkoxysilanes is developed. This process undergoes a direct intermolecular dehydrogenative Si-O coupling between dihydrosilanes with silanols or alocohols, giving access to a variety of highly functionalized chiral siloxanes and alkoxysilanes in decent yields with excellent stereocontrol, that significantly expand the chemical space of the silicon-centered chiral molecules. Further utility of this process was illustrated by the construction of CPL-active (circularly polarized luminescence) silicon-stereogenic alkoxysilane small organic molecules. Optically pure bis-alkoxysilane containing two silicon-stereogenic centers and three pyrene groups displayed a remarkable glum value with a high fluorescence quantum efficiency (glum = 0.011, φF = 0.55), which could have great potential application prospects in chiral organic optoelectronic materials.

Silicon-center chiral silicon-oxygen compound and preparation method thereof

-

Paragraph 0106-0109; 0111-0112; 0114, (2021/07/24)

The invention belongs to the field of chiral silicon synthesis, and discloses a silicon-center chiral silicon-oxygen compound. The compound has a structure represented by general formula I shown in the specification. In the formula I, X is Si(R)n or a formula also shown in the specification, R is selected from alkyl, cycloalkyl and aryl, R is selected from alkyl, substituted phenyl and aryl, R is selected from alkyl, phenyl and substituted phenyl, n is 3, the three R are the same or different, R is selected from hydrogen and (C1-C4) alkyl, m is selected from 0, 1, 2 and 3, and Y is selected from substituted phenyl, substituted pyrenyl, aryl, heteroaryl and cycloalkyl. The invention also discloses a preparation method of the compound. Various highly functionalized chiral siloxanes and silyl ethers are obtained with good chemical, regional and stereo control and high yield, the variety of silicon center chiral compounds is expanded, and the method has the advantages of high enantioselectivity, wide substrate application range, mild reaction conditions, atom economy and the like. In addition, the compound provided by the invention has a huge application prospect in chiral organic photoelectric materials.

Selective Manganese-Catalyzed Oxidation of Hydrosilanes to Silanols under Neutral Reaction Conditions

Wang, Kaikai,Zhou, Jimei,Jiang, Yuting,Zhang, Miaomiao,Wang, Chao,Xue, Dong,Tang, Weijun,Sun, Huamin,Xiao, Jianliang,Li, Chaoqun

supporting information, p. 6380 - 6384 (2019/05/06)

The first manganese-catalyzed oxidation of organosilanes to silanols with H2O2 under neutral reaction conditions has been accomplished. A variety of organosilanes with alkyl, aryl, alknyl, and heterocyclic substituents were tolerated, as well as sterically hindered organosilanes. The oxidation appears to proceed by a concerted process involving a manganese hydroperoxide species. Featuring mild reaction conditions, fast oxidation, and no waste byproducts, the protocol allows a low-cost, eco-benign synthesis of both silanols and silanediols.

Hydrogenation of silyl formates: sustainable production of silanol and methanol from hydrosilane and carbon dioxide

Koo, Jangwoo,Kim, Seung Hyo,Hong, Soon Hyeok

, p. 4995 - 4998 (2018/05/23)

A new process for simultaneously obtaining two chemical building blocks, methanol and silanol, was realized starting from silyl formates which can be derived from silane and carbon dioxide. Understanding the reaction mechanism enabled us to improve the reaction efficiency by the addition of a small amount of methanol.

Synthesis, characterization and catalytic oxidation of organosilanes with a novel multilayer polyoxomolybdate containing mixed-valence antimony

Wang, Yaping,Lu, Jingkun,Ma, Xinyi,Niu, Yanjun,Singh, Vikram,Ma, Pengtao,Zhang, Chao,Niu, Jingyang,Wang, Jingping

, p. 167 - 174 (2018/04/24)

Oxidation of organosilanes is one of the pivotal reactions in organic synthesis and the corresponding products of silanols are widely as raw materials in industrial processes. In this paper, a new type of polyoxomolybdate containing mixed-valence antimony, [SbVSbIII4Mo18O66]7? (1a), has been isolated as tetramethyl ammonium salt in aqueous solution. The compound was structurally characterized by FT-IR, XPRD, TG, XPS, ESI–MS etc. It is the first time that the containing mixed-valence antimony polyoxomolybdate was used as a heterogeneous catalyst to efficaciously catalyze the oxidation of organosilanes to silanols under mild reaction conditions. Furthermore, the catalyst was stable and maintained its catalytic activity after three reaction cycles.

Diamond-shaped [Ag4]4+ cluster encapsulated by silicotungstate ligands: Synthesis and catalysis of hydrolytic oxidation of silanes

Kikukawa, Yuji,Kuroda, Yoshiyuki,Yamaguchi, Kazuya,Mizuno, Noritaka

supporting information; experimental part, p. 2434 - 2437 (2012/05/05)

An Ag4 diamond is encapsulated by silicotungstate ligands in TBA8[Ag4(DMSO)2(γ-H2SiW 10O36)2]·2 DMSO·2 H2O (Ag4; DMSO=dimethyl sulfoxide, TBA=tetra-n-butylammonium), which was obtained by reaction of TBA4H4[γ-SiW10O 36] with AgOAc in an organic medium. Polyoxometalate Ag4 (see picture) selectively catalyzes hydrolytic oxidation of various silanes to the corresponding silanols in high yields (72-96 %). Copyright

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