182576-32-5Relevant academic research and scientific papers
Solution phase combinatorial chemistry. Discovery of novel polyazapyridinophanes with potent antibacterial activity by a solution phase simultaneous addition of functionalities approach
An, Haoyun,Cummins, Lendell L.,Griffey, Richard H.,Bharadwaj, Ramesh,Haly, Becky D.,Fraser, Allister S.,Wilson-Lingardo, Laura,Risen, Lisa M.,Wyatt, Jacqueline R.,Cook, P. Dan
, p. 3696 - 3708 (1997)
Chemical modification of pre-formed asymmetric polyazaphane scaffolds by simultaneous addition of functionality (letters) in solution has been developed for the preparation of tertiary nitrogen-based combinatorial chemistry libraries. This approach has so
Solution phase combinatorial chemistry. I. Synthesis of polyazacyclophane scaffolds and tertiary amine libraries
An, Haoyun,Cook, P. Dan
, p. 7233 - 7236 (2007/10/03)
Three novel unsymmetrical polyazacyclophane scaffolds 1-3 were efficiently synthesized in high yields by a new cyclization method followed by selective deprotection. Scaffold 2 was combinatorialized by solution phase simultaneous addition of functionaliti
