182624-80-2

Upstream product

• 127642-52-8 ethyl (E)-3-(2,2-dimethyl-1,3-dioxolan-4-yl)-2-methyl-2-propenoate 
• 182624-99-3 (3aS,6R,7S,7aS)-7-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-6-methoxymethoxymethyl-7a-methyl-hexahydro-isobenzofuran-1-one 
• 182624-74-4 (1R,2S,3S,4R)-3-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-2-methyl-5-oxo-bicyclo[2.2.2]octane-2-carboxylic acid ethyl ester 
• 182624-76-6 (1R,2S,3S,4S)-3-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-2-methyl-bicyclo[2.2.2]oct-5-ene-2-carboxylic acid ethyl ester 
• 182624-78-8 (3aS,6R,7S,7aS)-7-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-6-hydroxymethyl-7a-methyl-hexahydro-isobenzofuran-1-one 

Downstream Products

• 182625-00-9 2,2-Dimethyl-propionic acid (1S,2S,3S,4R)-3-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-hydroxymethyl-4-methoxymethoxymethyl-2-methyl-cyclohexylmethyl ester 
• 182624-86-8 (1S,2R,3S,4R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-3-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-4-methoxymethoxymethyl-2-methyl-cyclohexanecarbaldehyde 
• 182624-84-6 [(1S,2S,3S,4R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-3-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-4-methoxymethoxymethyl-2-methyl-cyclohexyl]-methanol 
• 182823-32-1 [(1R,2S,3S,4R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-3-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-4-methoxymethoxymethyl-2-methyl-cyclohexyl]-methanol 
• 182625-06-5 [(2E,6E)-(S)-8-((1R,2S,3S,4R)-3-Benzenesulfonylmethyl-2-benzyloxymethyl-3,4-dimethyl-cyclohexyl)-8-benzyloxymethoxy-2,6-dimethyl-octa-2,6-dienyloxy]-tert-butyl-dimethyl-silane 
• 182624-97-1 C₄₁H₅₃ClO₅S 
• 182625-07-6 (2E,6E)-(S)-8-((1R,2S,3S,4R)-3-Benzenesulfonylmethyl-2-benzyloxymethyl-3,4-dimethyl-cyclohexyl)-8-benzyloxymethoxy-2,6-dimethyl-octa-2,6-dien-1-ol 
• 182624-96-0 (2E,6E)-(S)-1-((1R,2S,3S,4R)-3-Benzenesulfonylmethyl-2-benzyloxymethyl-3,4-dimethyl-cyclohexyl)-8-(tert-butyl-dimethyl-silanyloxy)-3,7-dimethyl-octa-2,6-dien-1-ol 
• 182625-01-0 tert-Butyl-[(1R,2S,3R,6R)-2-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-3-methoxymethoxymethyl-1-methyl-6-phenylsulfanylmethyl-cyclohexylmethoxy]-dimethyl-silane 
• 182624-82-4 2,2-Dimethyl-propionic acid (1S,2S,3S,4R)-2-(tert-butyl-dimethyl-silanyloxymethyl)-3-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-4-methoxymethoxymethyl-2-methyl-cyclohexylmethyl ester 
• 182625-04-3 C₂₆H₃₆O₅S 
• 182624-92-6 (R)-4-((1S,2S,3R,6R)-2-Benzenesulfonylmethyl-6-methoxymethoxymethyl-2,3-dimethyl-cyclohexyl)-2,2-dimethyl-[1,3]dioxolane 
• 182624-94-8 (1R,2S,3S,4R)-3-Benzenesulfonylmethyl-2-benzyloxymethyl-3,4-dimethyl-cyclohexanecarbaldehyde 
• 182625-03-2 (R)-4-((1S,2S,3R,6R)-6-Methoxymethoxymethyl-2,3-dimethyl-2-phenylsulfanylmethyl-cyclohexyl)-2,2-dimethyl-[1,3]dioxolane 

Relevant academic research and scientific papers

Total synthesis of phomactin D

The first total synthesis of PAF antagonist marine diterpenoid phomactin D was achieved from L-ascorbic acid. This synthesis involves the formation of bicyclo[2.2.2]octane derivative 3 by the sequential Michael reaction, oxidative cleavage of the double bond of 4 and cyclization of sulfone 18.