Total synthesis of phomactin D

DOI: 10.1016/0040-4039(96)01585-7

Source and publish data:

Tetrahedron Letters p. 7107 - 7110 (1996)

Update date:2022-08-05

Topics:

Authors:

Miyaoka, Hiroaki

Saka, Yasuhiro

Miura, Shotaro

Yamada, Yasuji

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(96)01585-7

The first total synthesis of PAF antagonist marine diterpenoid phomactin D was achieved from L-ascorbic acid. This synthesis involves the formation of bicyclo[2.2.2]octane derivative 3 by the sequential Michael reaction, oxidative cleavage of the double bond of 4 and cyclization of sulfone 18.

Full text of DOI:10.1016/0040-4039(96)01585-7

Products guided by the article

Product name:[(1S,2S,3R,6S)-2-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-6-hydroxymethyl-3-methoxymethoxymethyl-1-methyl-cyclohexyl]-methanol

Cas No:182624-80-2

R&D Labs maybe for 182624-80-2

Hebei DaPeng Pharm & Chem Co., Ltd.

Contact:86-317-7298678,0576-88861898 88861908

Address:West Songmen Village, East Songmen Town, Wuqiao, Cangzhou, Hebei ,China
Aqua Chem Industry Co., Ltd

Contact:+86-515-88356562

Address:No.2, West Daqing Road, Yancheng, Jiangsu, China
Xi'an Yuri Solar Co., Ltd

website:https://www.yurisolar.com/en

Contact:86--18092602675

Address:No. 560, East Hangtian Road, Xi'an, China
LIDE PHARMACEUTICALS LIMITED

website:http://www.lidepharma.com

Contact:+86-25-58409506

Address:Chungking Express Nos.36 Nathan Road，Kowloon, HK
Changzhou Sunsheng Chem Co., Ltd

Contact:+1-(989)-854-0648

Address:No. 28 Yinshan Rd., Xixiashu Industrial Park

Relevant to this article

Synthesis of 1,2,4-trioxepanes via application of thiol-olefin Co-oxygenation methodology

Doi:10.1016/j.bmcl.2006.08.098
(2006)
Reversal of polarization in amidophosphines: Neutral- and anionic-κP coordination vs. anionic-κP,N coordination and the formation of nickelaazaphosphiranes

Doi:10.1039/b507040f
(2005)
REGIOSPECIFIC SYNTHESIS OF AROMATIC COMPOUNDS VIA ORGANOMETALLIC INTERMEDIATES. I. para-SUBSTITUTED BENZENES

Doi:10.1016/S0022-328X(00)99496-8
(1983)
Concise and stereoselective synthesis of the N₇-C₂₅ fragment of psymberin

Doi:10.1021/ol0520267
(2005)
Discovery and SAR of cyclic isothioureas as novel NPY Y₁ receptor antagonists

Doi:10.1016/j.bmcl.2009.09.048
(2009)
Molecular aggregations and supramolecular architectures of amphiphilic PEO₁₇-OPV₃ and its hybrid with silica

Doi:10.1039/b503393d
(2005)

Article Doi