182627-25-4

Basic information

• Product Name: phenyl (chloromethyl)(N-methyl-N-trimethylsilylamido)phosphonate
• Synonyms: phenyl (chloromethyl)(N-methyl-N-trimethylsilylamido)phosphonate
• CAS NO: 182627-25-4
• Molecular Weight: 291.79
• Mol File: 182627-25-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: phenyl (chloromethyl)(N-methyl-N-trimethylsilylamido)phosphonate(CAS DataBase Reference)
• NIST Chemistry Reference: phenyl (chloromethyl)(N-methyl-N-trimethylsilylamido)phosphonate(182627-25-4)
• EPA Substance Registry System: phenyl (chloromethyl)(N-methyl-N-trimethylsilylamido)phosphonate(182627-25-4)

Safety Data

• Hazardous Substances Data: 182627-25-4(Hazardous Substances Data)

Upstream product

• 920-68-3 heptamethyldisilazane 
• 39200-99-2 phenyl (chloromethyl)phosphonochloridate 

Downstream Products

• 10419-85-9 diphenyl (chloromethyl)phosphonate 

Relevant articles and documents

Synthesis and Properties of Some Derivatives of (Chloromethyl)phosphonic and Bis(chloromethyl)phosphinic Acids

(Chloromethyl)phosphonic(phosphinic) chlorides were reacted with primary amines and hepta-methyldisilazane to obtain the corresponding amides. The reaction of phenyl N-methyl-N-(trimethylsilyl)-(chloromethyl)phosphonamidate with phenyl isocyanate involves intermediate formation of phosphorylated urea which undergoes cyclization into 1,4,2-diazaphospholidin-5-one. The reaction with benzaldehyde occurs by β cleavage, yielding trimethylsilyl (chloromethyl)phosphonate. Phosphorylation of amides and silylamides of (chloromethyl)phosphonic(phosphinic) acids with four-coordinate phosphorus acid chlorides was studied.