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BENZO[1,3]DIOXOL-4-METHYLAMINE, scientifically known as 1-(2H-1,3-Benzodioxol-4-yl)methanamine, is a chemical compound belonging to the benzo[d][1,3]dioxole family. It is characterized by a phenethylamine core, a common structural feature in many psychoactive and stimulative substances. BENZO[1,3]DIOXOL-4-METHYLAMINE is typically found as a light brown to dark brown powder or solid and is primarily used in the industrial sector, particularly for chemical research purposes.

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  • 182634-34-0 Structure
  • Basic information

    1. Product Name: BENZO[1,3]DIOXOL-4-METHYLAMINE
    2. Synonyms: BENZO[1,3]DIOXOL-4-METHYLAMINE;1,3-Benzodioxole-4-methanamine;benzo[d][1,3]dioxol-4-ylmethanamine;2,3-(Methylenedioxy)benzylaMine;2H-1,3-Benzodioxol-4-ylMethanaMine
    3. CAS NO:182634-34-0
    4. Molecular Formula: C8H9NO2
    5. Molecular Weight: 151.16
    6. EINECS: 604-604-1
    7. Product Categories: N/A
    8. Mol File: 182634-34-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 85 °C(Press: 0.4 Torr)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.253±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C(protect from light)
    8. Solubility: N/A
    9. PKA: 9.16±0.29(Predicted)
    10. CAS DataBase Reference: BENZO[1,3]DIOXOL-4-METHYLAMINE(CAS DataBase Reference)
    11. NIST Chemistry Reference: BENZO[1,3]DIOXOL-4-METHYLAMINE(182634-34-0)
    12. EPA Substance Registry System: BENZO[1,3]DIOXOL-4-METHYLAMINE(182634-34-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 182634-34-0(Hazardous Substances Data)

182634-34-0 Usage

Uses

Used in Chemical Research:
BENZO[1,3]DIOXOL-4-METHYLAMINE is used as a research compound for [application reason] in the field of chemical research. Its unique structure and properties make it a valuable subject for scientific investigation and potential applications in various chemical processes.
Used in Industrial Applications:
BENZO[1,3]DIOXOL-4-METHYLAMINE is used as an industrial chemical for [application reason] in various industries. Its versatility and reactivity in chemical reactions contribute to its utility in the development of new materials and products.

Check Digit Verification of cas no

The CAS Registry Mumber 182634-34-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,2,6,3 and 4 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 182634-34:
(8*1)+(7*8)+(6*2)+(5*6)+(4*3)+(3*4)+(2*3)+(1*4)=140
140 % 10 = 0
So 182634-34-0 is a valid CAS Registry Number.

182634-34-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 1,3-benzodioxol-4-ylmethanamine

1.2 Other means of identification

Product number -
Other names benzo[1,3]dioxol-4-methylamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:182634-34-0 SDS

182634-34-0Relevant articles and documents

Modulators of protease activated receptors

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Page/Page column 32, (2018/02/20)

The present invention provides novel compounds of the Formula (I), pharmaceutical compositions comprising such compounds and methods for using such compounds as tools for biological studies or as agents or drugs for therapies such as metabolic syndrome, obesity, type II diabetes, fibrosis and cardiovascular diseases, whether they are used alone or in combination with other treatment modalities.

ARYL FLUOROETHYL UREAS ACTING AS ALPHA 2 ADRENERGIC AGENTS

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Page/Page column 29, (2008/12/07)

The invention provides well-defined aryl fluoroethyl ureas that are useful as selective alpha2 adrenergic agonists. As such, the compounds described herein are useful in treating a wide variety of disorders associated with modulation of alpha2 adrenergic receptors.

Pd(OAc)2-catalyzed carbonylation of amines

Orito, Kazuhiko,Miyazawa, Mamoru,Nakamura, Takatoshi,Horibata, Akiyoshi,Ushito, Harumi,Nagasaki, Hideo,Yuguchi, Motoki,Yamashita, Satoshi,Yamazaki, Tetsuro,Tokuda, Masao

, p. 5951 - 5958 (2007/10/03)

A phosphine-free catalytic system [Pd(OAc)2-Cu(OAc) 2-air] induced a substrate-specific carbonylation of amines in boiling toluene under CO gas (1 atm). Symmetrical N,N′-dialkylureas were obtained by the carbonylation of primary amines. N,N,N′-Trialkylureas were selectively formed by addition of a secondary amine to the above reaction vessel. Secondary amines did not give tetraalkylureas. However, dialkylamines with a phenyl group on their alkyl chains, such as N-monoalkylated benzylic amine or phenethylamine derivatives, underwent a direct aromatic carbonylation to afford five- or six-membered benzolactams. In the carbonylation, the chelation effect or steric repulsion between Pd(II) and the meta-substituent in the ortho-palladation and the ring sizes of cyclopalladation products that were formed prior to carbonylation were found to generate good site selectivity and increase the reaction rate. In contrast, carbonylation of ω- arylalkylamines with a hydroxyl group gave neither ureas nor benzolactams but instead produced 1,3-oxazolidinones smoothly. Hydrochlorides of amines also underwent carbonylation to afford the corresponding amides under the conditions used. This procedure made it possible to prepare ureas of amino acid esters and N-alkylcarbamates in practical yields.

Novel flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof

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Page/Page column 84, (2008/06/13)

The present invention relates to the discovery that certain non-naturally occurring, non-peptide amide compounds and amide derivatives, such as oxalamides, ureas, and acrylamides, are useful flavor or taste modifiers, such as a flavoring or flavoring agents and flavor or taste enhancer, more particularly, savory (the “umami” taste of monosodium glutamate) or sweet taste modifiers,—savory or sweet flavoring agents and savory or sweet flavor enhancers, for food, beverages, and other comestible or orally administered medicinal products or compositions.

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